Results 171 to 180 of about 5,038,638 (360)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A slacks-based measure of efficiency in data envelopment analysis
European Journal of Operational Research, 1997 K. Tone
semanticscholar +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The Equity-Efficiency Relationship: the Double Criterion versus Pareto-Efficiency [PDF]
The paper is devoted to the analysis of the equity-efficiency relationship from the standpoint of the proposed double criterion of efficiency as opposed to the criterion of Pareto-efficiency.
Gerhard Schwödiauer, Segii Arkhiiereiev
core
Returns to Buying Winners and Selling Losers: Implications for Stock Market Efficiency
, 1993 Narasimhan Jegadeesh, S. Titman
semanticscholar +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Efficiency Wages and Bargaining [PDF]
I argue that in contrast to the literature to date efficiency wage and bargaining solutions will typically be independent. If the bargained wage satisfies the efficiency wage constraint efficiency wages are irrelevant.
Frank Walsh
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Efficiency of EM Induction Permanent Magnets Pumps
The efficiency of EM induction pumps on permanent magnets are defined by their main constructive parameters the optimal values of which, in its turn, are depending on specified nominal productivity of pump (developed pressure head and provided flow rate)
Kravalis, Kalvis, Bucenieks, Imants
core
Technical Efficiency Evaluation: Naturally Dual! [PDF]
We provide a dual perspective on technical efficiency evaluation, in two respects. First, we build on the price assumptions implicitly associated with the notion of technical efficiency in a general equilibrium framework to characterize a set of ...
Tom Van Puyenbroeck, Laurens Cherchye
core