Generating evidence that meets the requirements of both regulatory agencies and HTA bodies
Beate Wieseler +2 more
doaj +1 more source
Entry Without Expression: Internalisation Does Not Predict mRNA Translation for Targeted Lipid Nanoparticles. [PDF]
Smyth CH +4 more
europepmc +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
A 4E (energy, exergy, environmental, and economic) evaluation of a solar air heater with airflow beneath a V-shaped perforated finned absorber. [PDF]
Shaaban FM +5 more
europepmc +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Hole Transport Layer-Free CsSnI <b><sub>3</sub></b> ‑Based Perovskite Solar Cells with WS <b><sub><sub>2</sub></sub> </b> Electron Transport Layer: Design, Simulation, and Performance Optimization. [PDF]
Uddin R, Duzkaya H.
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Polymer-Based Scale Inhibition of Calcium Sulfate Using Phosphino-Polycarboxylic Acid: Experimental Evaluation, RSM Modeling, and Process Optimization. [PDF]
Khormali A, Ahmadi S.
europepmc +1 more source

