Results 171 to 180 of about 4,250,837 (304)

Efficacy, Effectiveness, and Efficiency of Nurse-Led Interventions: Insights From a Critical Systematic Review. [PDF]

Nurs Inq
Fontanals-Jimenez A, Trapero-Bertran M, Insa-Calderón E.   +2 more
europepmc   +1 more source

Uptake Grant - Valid Evaluations - Multi-Year Humanitarian Financing Thematic Evaluation

, 2018
Between 2014 and 2018, Valid Evaluations conducted a thematic evaluation for DFID. The evaluation aimed to test whether the introduction of longer-term funding could help build resilience, and whether it provided better value for money.
Valid Evaluations (19347295)
core  

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

The carbon neutrality effect of green fiscal stimulus policy: City-level insights from the decarbonization-greenization nexus. [PDF]

iScience
Cheng S, Wang K, Chen X, Chen J.
europepmc   +1 more source

Energy Efficiency Board. 2016 Programs and Operations Report.

, 2017
Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Enhanced Line Search Improves Robustness and Efficiency of Pose Sampling in Protein-Ligand Docking. [PDF]

J Chem Theory Comput
Gaskin L, Welsch M, Kirchmair J, Kimiaei M.   +3 more
europepmc   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Beyond Time Saved: A Framework for Comprehensive Evaluation of AI Clinical Documentation. [PDF]

JMIR Med Inform
Sze Min EV.
europepmc   +1 more source

Efficient Evaluation of Aggregates on Bulk Types [PDF]

Electronic Workshops in Computing, 1995
Cluet, Sophie, Moerkotte, Guido
openaire   +3 more sources