Results 71 to 80 of about 4,250,837 (304)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

National Action Plan for Energy Efficiency, Chapter 6: Energy Efficiency Program Best Practices

, 2006
Chapter from the National Action Plan for Energy Efficiency documenting key findings from energy efficiency programs that have been successfully operating for many ...
National Action Plan for Energy Efficiency (U.S.)
core  

2021-03-11 Faculty Senate Evaluations Committee Meeting Minutes

, 2021
The Faculty Senate Evaluations Committee meeting minutes for March 11 ...
Morehead State University. Faculty Senate., Evaluations Committee.   +1 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Photocatalytic degradation of enrofloxacin with CoAl-LDH mediated persulfate system: Efficiency evaluations and reaction pathways

Emerging Contaminants
Residual enrofloxacin (ENR) exposed in aqueous environments is challenging to the ecosphere. In this work, a layered double hydroxide CoAl-LDH was used to activate the common oxidizing agent persulfate (PS) for photodegradation of ENR, and the ...
Yuxuan Zhang, Kai He, Long Chen, Wen Liu, Jinlong Yuan, Yaotong Gao, Yuanfeng Qi, Bingjun Liu   +7 more
doaj   +1 more source

EVALUATION OF REGIONAL EFFICIENCY DISPARITIES BY EFFICIENT FRONTIER ANALYSIS

Ekonomika, 2013
Abstract. The nonparametric methods, such as data envelopment analysis, free disposal hull and order-α frontier analysis, have been applied in this study to evaluate the efficient frontier which extends the application of the production function of regions.
Dzemydaitė, Giedrė, Galinienė, Birutė   +1 more
openaire   +4 more sources

Energy-Efficiency Program Evaluations: Opportunities for Learning and Inputs to Incentive Mechanisms [PDF]

We analyze the evaluations of California energy-efficiency programs to assess the effectiveness of these evaluations in: 1) improving our understanding of their performance and 2) providing a check on utility incentives to overstate energy savings.
Kaufman, Noah, Palmer, Karen
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Efficient Leasing of Automobiles Involved in International Cargo Transportation

Наука и техника, 2005
The paper proposes methodology for estimation of leasing transaction efficiency that includes development of qualitative criteria and quantitative evaluation.
R. B. Ivuts, S. Narushevich, P. Deschinsky   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source