Results 71 to 80 of about 349,145 (301)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Digital Technology as A Driver of Government Efficiency: An Analysis of Government Parastatals in Lagos State, Nigeria

open access: yesPerspektif: Jurnal Ilmu-ilmu Sosial
Digital technology is fast becoming a global phenomenon for efficient service delivery, both in private and public institutions. Developing nations have been increasing their investments in essential E-government administration systems.
Solomon Adejare Babarinde
doaj   +1 more source

New Secured E-Government Efficiency Model for Sustainable Services Provision

open access: yesJournal of Information Security and Cybercrimes Research, 2020
E-government projects in some developing countries face many challenges to provide sustainable services for e-efficiency. Literature shows that most governments suffer from lack of technology and restrictions associated with budgets and human resources ...
Youseef Alotaibi
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Komparasi tingkat efisiensi antara bank Syariah milik pemerintah dan privat serta pengaruh struktur kepemilikan terhadapnya

open access: yesJournal of Enterprise and Development, 2020
Numerous studies indicate that government control of a bank has a detrimental effect on its performance. Is this usually the case and does it apply to all types of banks? This is the research question.
Imam Haroki Enayatullah
doaj   +1 more source

Buyer Collusion and Efficiency of Government Intervention in Wheat Markets in Northern India: An Asymmetric Structural Auctions Analysis

open access: yesAmerican Journal of Agricultural Economics, 2004
This article uses auction theory to analyze wholesale markets for wheat in Northern India. This approach enables us to characterize the market in terms of buyer asymmetries, to detect the existence of collusion, and to quantify its impact on market ...
A. Banerji, J. Meenakshi
semanticscholar   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Experimental investigation on a diesel engine using waste cooking oil biodiesel-alcohol-diesel ternary blends with Al2O3 nanoparticles

open access: yesScientific Reports
The aim of this study is to examine the synergistic effect of a ternary blend of waste cooking oil biodiesel, pentanol, and diesel, combined with the catalytic activity of Al2O3 nanoparticles in a direct injection (DI) diesel engine.
Mark Sudarsanam   +8 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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