Results 171 to 180 of about 2,589,705 (354)

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

Evaluating feature extraction reproducibility across image biomarker standardization initiative‐compliant radiomics platforms using a digital phantom

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The aim of this study was to thoroughly analyze the reproducibility of radiomics feature extraction across three Image Biomarker Standardization Initiative (IBSI)‐compliant platforms using a digital phantom for benchmarking. It uncovers high consistency among common features while also pointing out the necessity for standardization ...
Han‐Back Shin   +5 more
wiley   +1 more source

Producing high quality cranial SRS plans with 4Pi planning technique in a commercial clinical solution

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To generate high‐quality stereotactic radiosurgery (SRS) plans for single cranial lesions using 4Pi planning technique and compare these to our clinical “status quo” plans. Methods Eighteen vestibular schwannoma (VS) patients previously planned with Varian Eclipse RapidArc and treated on a Varian TrueBeam using 6FFF MV photon beams ...
Ganesh Narayanasamy   +4 more
wiley   +1 more source

Using Coordinated Transmission with Energy Efficient Ethernet [PDF]

open access: bronze, 2011
Pedro Reviriego   +3 more
openalex   +1 more source

Energy dependence of the GAFCHROMIC LD‐V1 in the diagnostic radiographic modalities

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract The GAFCHROMIC LD‐V1 radiochromic film is widely used in dosimetry because it can provide high‐resolution two‐dimensional dose distributions without processing. This study aimed to evaluate the response characteristics at different effective energies, from the low‐energy range of mammography to the high‐energy range of computed tomography. Net
Tatsuhiro Gotanda   +9 more
wiley   +1 more source

Long‐term stability analysis of beam shape in a robotic radiosurgery system

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aimed to investigate the long‐term stability of CyberKnife beam profile parameters and assess their compliance with existing quality assurance (QA) guidelines. We evaluated beam profiles in both standard and diagonal planes over 3.5 years post‐installation to detect potential issues and ensure consistent beam quality.
Ryoichi Hinoto   +4 more
wiley   +1 more source

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