Results 81 to 90 of about 347,806 (306)

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

Real Estate Market Efficiency: A Survey of Literature [PDF]

open access: yes
In this paper, we discuss the question whether or not the real estate market is efficient. We define market efficiency and the efficient market hypothesis as it had been developed in the literature on financial markets.
Gunther Maier, Shanaka Herath
core  

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan   +16 more
wiley   +1 more source

Performance Anomalies and Determinants of Equity Funds: Evidence from Türkiye

open access: yesEkonomi, Politika & Finans Araştırmaları Dergisi
This study aims to contribute to the literature by examining whether the returns of equity funds represent a new source of anomaly within the framework of the Efficient Markets Hypothesis.
Aykan Coşkun
doaj   +1 more source

Market Efficiency and News Dynamics: Evidence from International Equity Markets

open access: yesEconomies, 2019
This paper examines the efficient market hypothesis by applying monthly data for 15 international equity markets. With the exceptions of Canada and the U.S., the null for the absence of autocorrelations of stock returns is rejected for 13 out of 15 ...
Thomas C. Chiang
doaj   +1 more source

Efficiency versus Robustness of Markets - Why improving market efficiency should not be the only objective of market regulation [PDF]

open access: yes
The efficiency of capital markets has been questioned almost as long as the efficient market hypothesis had been worked out. Numerous critics have been formulated against this hypothesis, questioning notably the behavioural assumptions underlying the ...
Christoph Weber
core  

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Multiscale Analysis of the Predictability of Stock Returns

open access: yesRisks, 2015
Due to the strong complexity of financial markets, economics does not have a unified theory of price formation in financial markets. The most common assumption is the Efficient-Market Hypothesis, which has been attacked by a number of researchers, using ...
Paweł Fiedor
doaj   +1 more source

Random walks in asian foreign exchange markets:evidence from new multiple variance ratio tests [PDF]

open access: yes
This paper revisits the random walk hypothesis for ten Pacific Basin foreign exchange markets. The results suggest that the null hypothesis of random walk is rejected based on the Lo-MacKinlay variance ratio tests, under conditions of both ...
Shyh-wei Chen
core  

Market efficiency in the emerging securitized real estate markets [PDF]

open access: yes, 2010
This paper tests the random walk hypothesis and market efficiency for twelve emerging as well as for four developed securitized real estate markets from 1992 to 2009.
Schindler, Felix
core   +2 more sources

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