Results 51 to 60 of about 7,435,185 (311)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Highly Efficient Circularly Polarized Near-infrared Phosphorescence in Both Solution and Aggregate [PDF]

Circularly polarized phosphorescence (CPP) is a spin-forbidden radiative process with chiroptical activity. The CPP mechanism is far from comprehensively understood, mainly due to the limited examples of efficient triplet emission from small chiral ...
Ben Zhong, Tang, Qian, Wu, Zheng, Zhao, Parvej, Alam, Lixun, Zhu, Yong, Liu, Yu, Xiong, Dan, Liu, Wenjin, Wang, Zhan , Yang, Bo, Wu, Kaiwen, Wu, Shuai, Chang, Zijie, Qiu   +13 more
core   +1 more source

Time-Dependent Restoration Routing Problem: An Efficient Initial Solution

Findings, 2022
We propose a time-dependent variant of the restoration routing problem scheduling restoration tasks for each crew given a limited time horizon. The model provides a feasible initial solution for real-world restoration crew routing problems.
Saviz Saei, Nazanin Tajik
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Sensitivity analysis of efficient solution in vector MINMAX boolean programming problem [PDF]

Computer Science Journal of Moldova, 2002
We consider a multiple criterion Boolean programming problem with MINMAX partial criteria. The extreme level of independent perturbations of partial criteria parameters such that efficient (Pareto optimal) solution preserves optimality was obtained.
Vladimir A. Emelichev, Vitaly N. Krichko, Yury V. Nikulin   +2 more
doaj   +2 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

An efficient confidentiality protection solution for pub/sub system

Cybersecurity, 2023
Publish/subscribe(pub/sub) systems are widely used in large-scale messaging systems due to their asynchronous and decoupled nature. With the population of pub/sub cloud services, the privacy protection problem of pub/sub systems has started to emerge ...
Jinglei Pei, Yuyang Shi, Qingling Feng, Ruisheng Shi, Lina Lan, Shui Yu, Jinqiao Shi, Zhaofeng Ma   +7 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

A rational deferred correction approach to parabolic optimal control problems [PDF]

, 2016
The accurate and efficient solution of time-dependent PDE-constrained optimization problems is a challenging task, in large part due to the very high dimension of the matrix systems that need to be solved.
Stefan Güttel, John W Pearson, Pearson, John W., Güttel, Stefan, Güttel, Stefan; id_orcid, Pearson, John W   +5 more
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source