Results 281 to 290 of about 284,066 (339)
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
wiley +1 more source
Abstract Objective This study evaluates the diagnostic performance of contrast‐enhanced ultrasound (CEUS) for improving diagnosis of adnexal torsion in women with acute abdominal pain. Methods This was a pilot study of the diagnostic accuracy of CEUS for the detection of adnexal torsion.
Anne‐Laure Fijean+5 more
wiley +1 more source
Electrical Impedance Tomography in Medical Applications: Brain and Lung
The clinical focus of EIT technology lies in lung function monitoring and neurological diseases, while also exploring new scenarios such as abdominal hemorrhage detection. Technological breakthroughs include the development of wearable devices and the optimization of hardware architecture.
Sibo Lian+4 more
wiley +1 more source
ABSTRACT This paper reports a case of Chlamydia psittaci pneumonia and pulmonary aspergillosis with concurrent liver injury. The patient was admitted to the hospital with coughing, expectoration, and fever for 5 days. Laboratory tests upon admission revealed abnormalities in liver function.
Chang Song+5 more
wiley +1 more source
This study systematically evaluated multiple machine learning models to predict short‐term adverse prognosis in neonatal bacterial meningitis using a retrospective cohort of 433 infants. The logistic regression model, combining mRMR‐selected and clinically prioritized variables, demonstrated optimal predictive performance (AUC = 0.908).
Ying Chen+8 more
wiley +1 more source
The role of child language ability and parental mentalization in early child dysregulation
Abstract Dysregulation in early childhood is associated with increased vulnerability to psychopathology and poor psychosocial outcomes. While there is evidence that both child language ability and parental mentalization are associated with dysregulation in early childhood, there is little understanding of the relationships between these variables, and ...
Sara Cibralic+6 more
wiley +1 more source
Building a culture of connection in early childhood education: The Hand in Hand Foundations Course
Abstract Healthy early childhood development unfolds in the context of relationships with important caregivers, including early educators. Grounded in the evidence on early relational health, the 8‐week Hand in Hand Foundations Course for Early Childhood Educators teaches a novel connection‐based approach to understanding and responding to young ...
Angela Sillars+6 more
wiley +1 more source
Organoid‐tissue extracellular vesicles
Abstract Extracellular vesicles (EVs) are lipid bilayer structures secreted by cells that act as intercellular messengers. Tissue‐derived EVs (TEVs), harvested from the tissue interstitium, directly reflect the actual physiological or pathological state of the tissue microenvironment.
Han Liu+6 more
wiley +1 more source
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li+5 more
wiley +1 more source