Results 11 to 20 of about 304 (88)

Telomere Length, Epigenetic Age Acceleration, and Mortality Risk in US Adult Populations: An Additive Bayesian Network Analysis. [PDF]

open access: yesAging Cell
Epigenetic DNA methylation‐based (DNAm) clocks, particularly GrimAge epigenetic age acceleration, outperform telomere length in predicting mortality across three US cohorts. Using Additive Bayesian Networks, we uncovered complex links among biological aging markers, sex, race, and mortality risk, highlighting the utility of DNAm‐based biomarkers in ...
Beydoun MA   +11 more
europepmc   +2 more sources

Roles of non‐coding RNAs in eye development and diseases

open access: yesWIREs RNA, Volume 14, Issue 5, September/October 2023., 2023
ncRNAs participate in different ocular diseases and eye development. Abstract The prevalence of ocular disorders is dramatically increasing worldwide, especially those that cause visual impairment and permanent loss of vision, including cataract, glaucoma, age‐related macular degeneration, and diabetic retinopathy.
Xinrui Shi   +6 more
wiley   +1 more source

COGNITION, OPTIMISM, AND THE FORMATION OF AGE‐DEPENDENT SURVIVAL BELIEFS

open access: yesInternational Economic Review, Volume 62, Issue 2, Page 887-918, May 2021., 2021
Abstract This article investigates the roles of psychological biases for deviations between subjective survival beliefs (SSBs) and objective survival probabilities. We model these deviations through age‐dependent inverse S‐shaped probability weighting functions.
Nils Grevenbrock   +3 more
wiley   +1 more source

Transcriptome analysis of the zebrafish atoh7−/− Mutant, lakritz, highlights Atoh7‐dependent genetic networks with potential implications for human eye diseases

open access: yesFASEB BioAdvances, Volume 2, Issue 7, Page 434-448, July 2020., 2020
Abstract Expression of the bHLH transcription protein Atoh7 is a crucial factor conferring competence to retinal progenitor cells for the development of retinal ganglion cells. Several studies have emerged establishing ATOH7 as a retinal disease gene. Remarkably, such studies uncovered ATOH7 variants associated with global eye defects including optic ...
Giuseppina Covello   +13 more
wiley   +1 more source

Fully Autonomous Orbit Determination and Synchronization for Satellite Navigation and Communication Systems in Halo Orbits [PDF]

open access: yes, 2023
This paper presents a solution for autonomous orbit determination and time synchronization of spacecraft in Halo orbits around Lagrange points using inter-satellite links.
Leonardi M., Sirbu G.
core   +1 more source

Undifferenced and Uncombined GNSS Time Transfer and its Space Applications [PDF]

open access: yes, 2023
This thesis presents a framework for developing a state-of-the-art undifferenced and uncombined (UDUC) time transfer technique for space applications.
Mi, Xiaolong
core  

Fragment‐Based Drug Discovery of Novel High‐affinity, Selective, and Anti‐inflammatory Inhibitors of the Keap1‐Nrf2 Protein‐Protein Interaction

open access: yesAngewandte Chemie, Volume 137, Issue 39, September 22, 2025.
We developed potent and selective noncovalent Keap1‐Nrf2 inhibitors through a structure‐guided fragment‐based approach. These nanomolar inhibitors activate Nrf2‐controlled genes, suppress inflammation via NLRP3 and STING pathways, and exhibit distinct transcriptional profiles compared to covalent Nrf2 activators, offering promising chemical probes and ...
Chunyu Lin   +23 more
wiley   +2 more sources

Approximate analytic expressions using Stokes model for tokamak polarimetry and their range of validity [PDF]

open access: yes, 2019
The analysis of the polarimetry measurements has the aim of validating models (De Marco and Segre 1972 Plasma Phys. 14 245), with a careful attention to the clarification of their limits of application.
Orsitto, F P, Segre, S E, Subba, F
core   +1 more source

Terrestrial Very-Long-Baseline Atom Interferometry:Workshop Summary [PDF]

open access: yes, 2023
This document presents a summary of the 2023 Terrestrial Very-Long-Baseline Atom Interferometry Workshop hosted by CERN. The workshop brought together experts from around the world to discuss the exciting developments in large-scale atom interferometer ...
Abend, Sven   +252 more
core   +1 more source

Research on the joint fluctuation laws between locational marginal price and renewables based on complex networks: A case study in Independent System Operator New England

open access: yesEnergy Science &Engineering, Volume 7, Issue 6, Page 2866-2883, December 2019., 2019
Complex network theory is adopted to provide a statistical perspective rather than a causal perspective for study. Coarse‐grained method is conducted to simplify multiple time series into joint fluctuation patterns, which is different from traditional autoregressive and regression analysis.
Ding Liu   +3 more
wiley   +1 more source

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