Results 231 to 240 of about 368,793 (264)
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Nature Reviews Cancer, 2021
Gao, Xia, Li, Zhang et al. show that a circular RNA-encoded variant of E-Cadherin stimulates EGFR signalling independently of EGF, and contributes to glioblastoma tumorigenesis and anti-EGFR therapy resistance.
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Gao, Xia, Li, Zhang et al. show that a circular RNA-encoded variant of E-Cadherin stimulates EGFR signalling independently of EGF, and contributes to glioblastoma tumorigenesis and anti-EGFR therapy resistance.
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European Journal of Cancer, 2001
Elevated levels of the epidermal growth factor receptor (EGFR), a growth-factor-receptor tyrosine kinase, and/or its cognate ligands have been identified as a common component of multiple cancer types and appear to promote solid tumour growth. This article examines the relationship between EGFR expression and cancer prognosis based on literature ...
R I, Nicholson, J M, Gee, M E, Harper
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Elevated levels of the epidermal growth factor receptor (EGFR), a growth-factor-receptor tyrosine kinase, and/or its cognate ligands have been identified as a common component of multiple cancer types and appear to promote solid tumour growth. This article examines the relationship between EGFR expression and cancer prognosis based on literature ...
R I, Nicholson, J M, Gee, M E, Harper
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Anti-EGFR–mediated radiosensitization as a result of augmented EGFR expression
International Journal of Radiation Oncology*Biology*Physics, 2004Elevated epidermal growth factor receptor (EGFR) expression has correlated with a poor prognosis after standard treatment of several malignancies. However, it is not clear whether the absolute level of EGFR expression affects the radiosensitizing properties of anti-EGFR treatments. A better understanding of this question would be helpful for the design
James A, Bonner +6 more
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Applied Immunohistochemistry & Molecular Morphology, 2007
Immunohistochemistry is widely used to assess epidermal growth factor receptor (EGFR) expression on colorectal carcinomas to select patients for treatment with cetuximab, an anti-EGFR antibody. The data comparing different commercial EGFR antibodies is limited, and no cost comparisons have been made.
Anne F, Buckley, Sanjay, Kakar
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Immunohistochemistry is widely used to assess epidermal growth factor receptor (EGFR) expression on colorectal carcinomas to select patients for treatment with cetuximab, an anti-EGFR antibody. The data comparing different commercial EGFR antibodies is limited, and no cost comparisons have been made.
Anne F, Buckley, Sanjay, Kakar
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EGFR mutations and EGFR tyrosine kinase inhibitors
The Lancet Oncology, 2015Valter, Torri +2 more
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Lung Cancer
In EGFR-mutated lung adenocarcinoma (EGFRm LUAD), EGFR mutations do not necessarily result in increased EGFR expression (EGFR-exp), which differs among patients. However, the factors influencing EGFR-exp and the impact of EGFR-exp on tumor characteristics in patients with EGFRm LUAD remain unclear.Whole-exome and RNA sequencing were performed for ...
Masahiro Torasawa +23 more
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In EGFR-mutated lung adenocarcinoma (EGFRm LUAD), EGFR mutations do not necessarily result in increased EGFR expression (EGFR-exp), which differs among patients. However, the factors influencing EGFR-exp and the impact of EGFR-exp on tumor characteristics in patients with EGFRm LUAD remain unclear.Whole-exome and RNA sequencing were performed for ...
Masahiro Torasawa +23 more
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CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
Cancer Cell, 2023Thiruvengadam Arumugam +2 more
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EGFR signaling in renal fibrosis
Kidney International Supplements, 2014Na Liu, Shougang Zhuang
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