Results 61 to 70 of about 545,624 (314)
Journal of Physical Fitness and Sports Medicine, 2017 Renalase is a recently discovered flavin adenine dinucleotide (FAD)-dependent soluble monoamine oxidase. It is expressed principally in the kidney, but its expression in the heart, brain, and skeletal muscle has also been confirmed.
Yasuko Yoshida +6 more
doaj +1 more source
Journal of experimental & clinical cancer research : CR, 2021 Cetuximab and panitumumab are monoclonal antibodies (mAbs) against epidermal growth factor receptor (EGFR) that are effective agents for metastatic colorectal cancer (mCRC). Cetuximab can prolong survival by 8.2 months in RAS wild-type (WT) mCRC patients.
Jing Zhou, Q. Ji, Qi Li
semanticscholar +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2021 Febriana M Puspita,1 Em Yunir,2 Putri S Agustina,1 Rani Sauriasari1 1Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; 2Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, IndonesiaCorrespondence: Rani ...
Puspita FM +3 more
doaj
The Role of EREG/EGFR Pathway in Tumor Progression
International Journal of Molecular Sciences, 2021 Aberrant activation of the epidermal growth factor receptor (EGFR/ERBB1) by erythroblastic leukemia viral oncogene homolog (ERBB) ligands contributes to various tumor malignancies, including lung cancer and colorectal cancer (CRC).
Wan-Li Cheng +7 more
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Prognostic Factors in Patients with Advanced Lung Adenocarcinoma Treated with Icotinib
Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the relationship between the treatment of EGFR-TKI icotinib and the prognosis of advanced lung adenocarcinoma patients with EGFR mutation.
ZHANG Hongbin +8 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Regulation of Fibrotic Processes in the Liver by ADAM Proteases
Cells, 2019 Fibrosis in the liver is mainly associated with the activation of hepatic stellate cells (HSCs). Both activation and clearance of HSCs can be mediated by ligand−receptor interactions.
Dirk Schmidt-Arras, Stefan Rose-John
doaj +1 more source
Role of EGFR Juxtamembrane Domain in EGFR Activation [PDF]
Biophysical Journal, 2011 The intracellular juxtamembrane domain of several receptor tyrosine kinases (RTKs) has been proposed to play an autoinhibitory role. The epidermal growth factor receptor (EGFR) has been widely used as a model in studies of the RTK activation mechanism.
He, Lijuan +2 more
openaire +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source