Results 51 to 60 of about 785,489 (353)

The Role of EREG/EGFR Pathway in Tumor Progression

International Journal of Molecular Sciences, 2021
Aberrant activation of the epidermal growth factor receptor (EGFR/ERBB1) by erythroblastic leukemia viral oncogene homolog (ERBB) ligands contributes to various tumor malignancies, including lung cancer and colorectal cancer (CRC).
Wan-Li Cheng, P. Feng, Kang-Yun Lee, Kuan‐Yuan Chen, Wei-Lun Sun, Nguyen Van Hiep, C. Luo, Sheng-Ming Wu   +7 more
semanticscholar   +1 more source

Preliminary Study on Detection of Circulating Tumor Cells in Lung Cancer by EGFR/Vimentin/Folic Acid Magnetic Sphere

Chinese Journal of Lung Cancer, 2020
Background and Objective Circulating tumor cells (CTC) play an important role in the screening and prognosis of lung cancer, but the low efficiency and specificity of CTC isolation obviously restrict its clinical application. The purpose of this study is
Guolei LI, Yun WANG, Guoliang TAN, Yuan LIU, Zhao XU, Hao FENG, Wei XING, Zhifeng XU   +7 more
doaj   +1 more source

Silenced Expression of NFKBIA in Lung Adenocarcinoma Patients with a Never-smoking History [PDF]

, 2013
Nuclear factor of κ-light polypeptide gene enhancer in B cells inhibitor α (NFKBIA), which is a tumor suppressor gene, was found to be silenced in lung adenocarcinomas.
Asano, Hiroaki, Furukawa, Masashi, Ichimura, Kouichi, Maki, Yuho, Miyoshi, Shinichiro, Muraoka, Takayuki, Shien, Kazuhiko, Soh, Junichi, Tanaka, Norimitsu, Toyooka, Shinichi, Tsukuda, Kazunori, Ueno, Tsuyoshi, Yamamoto, Hiromasa   +12 more
core   +1 more source

The effect of rural-to-urban migration on renal function in an Indian population: cross-sectional data from the Hyderabad arm of the Indian Migration Study. [PDF]

, 2013
BACKGROUND: Urban migration is associated with an increased risk of hypertension, obesity and diabetes in Indian migrants. This study assessed the relationship between internal migration and renal function in the Hyderabad arm of the Indian Migration ...
Bailey, Phillippa K, Ben-Shlomo, Yoav, Ebrahim, Shah, Kinra, Sanjay, Kuper, Hannah, Nitsch, Dorothea, Radhakrishna, KV, Tomson, Charles RV   +7 more
core   +2 more sources

Renal Resistive İndeks’in Hafif Orta Böbrek Yetersizliği Olan Koroner Arter Hastalarında Hastalık Şiddetini Belirlemedeki Yeri

Ankara Medical Journal, 2016
Amaç: Çalışmamızda hafif orta renal yetersizliği olan hastalarda renal resistive indeksini (RRİ)saptayarak bunun renal fonksiyonlar ve koroner arter hastalığının (KAH) şiddetiyle ilişkisini araştırdık.Materyal ve Metot: Çalışmaya koroner angiografisi ...
Bircan Alan, Adem Aktan, Abdurrahim Dusak   +2 more
doaj   +1 more source

Nanobody-targeted photodynamic therapy for the treatment of feline oral carcinoma: a step towards translation to the veterinary clinic

Nanophotonics, 2021
Nanobody-targeted photodynamic therapy (NB-PDT) has been developed as a potent and tumor-selective treatment, using nanobodies (NBs) to deliver a photosensitizer (PS) specifically to cancer cells. Upon local light application, reactive oxygen species are
Beltrán Hernández Irati, Grinwis Guillaume C.M., Di Maggio Alessia, van Bergen en Henegouwen Paul M.P., Hennink Wim E., Teske Erik, Hesselink Jan W., van Nimwegen Sebastiaan A., Mol Jan A., Oliveira Sabrina   +9 more
doaj   +1 more source

Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure. [PDF]

, 2019
BACKGROUND: Moderate and moderately severe renal impairment are common in patients with heart failure and reduced ejection fraction, but whether beta-blockers are effective is unclear, leading to underuse of life-saving therapy.
Andersson, B, Anker, SD, Beta-Blockers in Heart Failure Collaborative Group, Böhm, M, Cleland, JGF, Coats, AJS, Damman, K, Flather, MD, Gill, SK, Holmes, J, Kjekshus, J, Kotecha, D, Manzano, L, McMurray, JJV, Packer, M, Redon, J, Rigby, AS, Rosano, G, Ruschitzka, F, van Veldhuisen, DJ, von Lueder, TG, Wedel, H, Wikstrand, J   +22 more
core   +8 more sources

Elevated homocysteine and differential risks of the renal function decline in hypertensive patients

Clinical and Experimental Hypertension, 2020
Importance In several studies, homocysteine (hcy) is a documented risk for predicting renal function decline. The differential effects between various levels of hcy have yet to be quantified.
Chunlei Liu, Lin Lin, Rui Xu
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

OncoImmunology, 2017
Recent treatments of leukemias with chimeric antigen receptor (CAR) expressing T cells underline their impressive therapeutic potential. However, once adoptively transferred into patients, there is little scope left to shut them down after elimination of
Susann Albert, Claudia Arndt, Anja Feldmann, Ralf Bergmann, Dominik Bachmann, Stefanie Koristka, Florian Ludwig, Pauline Ziller-Walter, Alexandra Kegler, Sebastian Gärtner, Marc Schmitz, Armin Ehninger, Marc Cartellieri, Gerhard Ehninger, Hans-Jürgen Pietzsch, Jens Pietzsch, Jörg Steinbach, Michael Bachmann   +17 more
doaj   +1 more source