Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming. [PDF]
, 2016 The impact of EGFR-mutant NSCLC precision therapy is limited by acquired resistance despite initial excellent response. Classic studies of EGFR-mutant clinical resistance to precision therapy were based on tumor rebiopsies late during clinical tumor ...
Bagai, Rakesh +14 more
core +1 more source
Regulation of Fibrotic Processes in the Liver by ADAM Proteases
Cells, 2019 Fibrosis in the liver is mainly associated with the activation of hepatic stellate cells (HSCs). Both activation and clearance of HSCs can be mediated by ligand−receptor interactions.
Dirk Schmidt-Arras, Stefan Rose-John
doaj +1 more source
Prognostic Factors in Patients with Advanced Lung Adenocarcinoma Treated with Icotinib
Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the relationship between the treatment of EGFR-TKI icotinib and the prognosis of advanced lung adenocarcinoma patients with EGFR mutation.
ZHANG Hongbin +8 more
doaj +1 more source
Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study. [PDF]
, 2020 Background:Observational studies relying on clinically obtained data have shown that acute kidney injury (AKI) is linked to accelerated chronic kidney disease (CKD) progression.
Anderson, Amanda H +21 more
core
NRP1 promotes prostate cancer progression via modulating EGFR-dependent AKT pathway activation [PDF]
, 2023 Peng Zhang +5 more
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Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study [PDF]
, 2016 Female renal transplant recipients of childbearing age may ask what the outcomes are for pregnancy and whether pregnancy will affect graft function. We analyzed obstetric and transplant outcomes among renal transplant recipients in our center who have ...
Brennand, Janet E. +6 more
core +1 more source
A promising new cancer marker: Long noncoding RNA EGFR-AS1 [PDF]
, 2023 Danhua Zhu +5 more
openalex +1 more source
Сибирский онкологический журнал, 2018 Activating mutations of EGFR are associated with sensitivity of non-small cell lung cancer (NSCLC ) to tyrosine kinase inhibitors (TKI). Liquid biopsy using circulating cell-free tumor DNA (cfDNA) is proposed in cases when formalin fixed paraffin ...
V. A. Shamanin +6 more
doaj +1 more source
Türk Patoloji Dergisi, 2020 Objective: Basal markers [cytokeratin 5/6 (CK5/6) and epidermal growth factor receptor (EGFR)] are used in identifying the basal-like breast carcinoma subtype, which is associated with a poor prognosis.
Fikret DIRILENOĞLU +3 more
doaj +1 more source
Indian Journal of Endocrinology and Metabolism, 2021 Objectives: This meta-analysis of randomized clinical trials (RCT) intends to evaluate the efficacy of DPP4 Inhibitors (DPP4I) compared with placebo, other antidiabetics (or DPP4I) on renal outcomes, adverse events (AEs), and all-cause mortality. Methods:
Saikat K Dalui +5 more
doaj +1 more source