Results 261 to 270 of about 545,624 (314)
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EGFR is going circular

Nature Reviews Cancer, 2021
Gao, Xia, Li, Zhang et al. show that a circular RNA-encoded variant of E-Cadherin stimulates EGFR signalling independently of EGF, and contributes to glioblastoma tumorigenesis and anti-EGFR therapy resistance.
openaire   +2 more sources

Clonal dominance of EGFR and efficacy of EGFR-tyrosine kinase inhibitors (EGFR-TKIs) in NSCLC.

Journal of Clinical Oncology, 2020
e21501 Background: Though EGFR mutations in lung cancer are identified most often on the trunks of tumor phylogenetic trees in early stage, whether EGFR would always be the dominant clone in the advanced stage is unknown, as cancer evolution often follows a branched trajectory, with divergent subclones evolving simultaneously.
Xinghao Ai   +14 more
openaire   +1 more source

EGFR and cancer prognosis

European Journal of Cancer, 2001
Elevated levels of the epidermal growth factor receptor (EGFR), a growth-factor-receptor tyrosine kinase, and/or its cognate ligands have been identified as a common component of multiple cancer types and appear to promote solid tumour growth. This article examines the relationship between EGFR expression and cancer prognosis based on literature ...
R I, Nicholson, J M, Gee, M E, Harper
openaire   +2 more sources

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

Science, 2004
J. Paez   +16 more
semanticscholar   +1 more source

Overcoming therapy resistance in EGFR-mutant lung cancer

Nature Cancer, 2021
A. Passaro, P. Jänne, T. Mok, S. Peters
semanticscholar   +1 more source

EGFR activation limits the response of liver cancer to lenvatinib

Nature, 2021
Haojie Jin   +30 more
semanticscholar   +1 more source

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial.

The Lancet Oncology, 2012
R. Rosell   +56 more
semanticscholar   +1 more source

EGFR mutations and EGFR tyrosine kinase inhibitors

The Lancet Oncology, 2015
Valter, Torri   +2 more
openaire   +2 more sources

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study.

The Lancet Oncology, 2011
Caicun Zhou   +22 more
semanticscholar   +1 more source

Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR–STAT3 signalling

Nature Cell Biology, 2021
Xinya Gao   +15 more
semanticscholar   +1 more source

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