Results 71 to 80 of about 4,481,653 (293)

Patterned Fluidity of Chinese Ethnic Identity: Networks, Time, and Place

SAGE Open, 2017
This study tests the salience/prominence of Chinese ethnic identity by applying identity theory, social identity theory, and social network analysis.
Cynthia Baiqing Zhang
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Assessing Ego-Centered Social Networks in formr: A Tutorial

Advances in Methods and Practices in Psychological Science, 2021
In psychological science, ego-centered social networks are assessed to investigate the patterning and development of social relationships. In this approach, a focal individual is typically asked to report the people they interact with in specific ...
Louisa M. Reins, Ruben C. Arslan, Tanja M. Gerlach   +2 more
doaj   +1 more source

Ego-centered networks and the ripple effect [PDF]

Social Networks, 2003
7 pages, 4 figures, 1 ...
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Maximally efficient prediction in the early fly visual system may support evasive flight maneuvers.

PLoS Computational Biology, 2021
The visual system must make predictions to compensate for inherent delays in its processing. Yet little is known, mechanistically, about how prediction aids natural behaviors.
Siwei Wang, Idan Segev, Alexander Borst, Stephanie Palmer   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Investigating ego modules and pathways in osteosarcoma by integrating the EgoNet algorithm and pathway analysis

Brazilian Journal of Medical and Biological Research
Osteosarcoma (OS) is the most common primary bone malignancy, but current therapies are far from effective for all patients. A better understanding of the pathological mechanism of OS may help to achieve new treatments for this tumor.
X.Y. Chen, Y.H. Chen, L.J. Zhang, Y. Wang, Z.C. Tong   +4 more
doaj   +1 more source

Dynamic Credit Quality Evaluation with Social Network Data

Journal of Applied Mathematics, 2019
We investigate the filtering problem where the borrower’s time varying credit quality process is estimated using continuous time observation process and her (in this paper we refer to the borrower as female and the lender as male) ego-network data.
Stanley Sewe, Philip Ngare, Patrick Weke
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source