Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences [PDF]
External guide sequence (EGS) RNAs are associated with ribonuclease P (RNase P), a tRNA processing enzyme, and represent promising agents for gene-targeting applications as they can direct RNase-P-mediated cleavage of a target mRNA.
Wei Li +9 more
doaj +4 more sources
Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High-Accuracy Breeding Value Prediction Without Compromising Embryo Survival. [PDF]
A diameter‐guided workflow was established to define the appropriate trophectoderm (TE) biopsy area window for bovine blastocysts, with the aim of balancing embryo viability and genotyping reliability. After TE biopsy, sampled cells were subjected to DNA amplification and genomic evaluation, while the corresponding biopsied embryos were transferred to ...
Zhang J +12 more
europepmc +2 more sources
Differenza sessuale e ontologia
The paper aims to underline and develop a possible – and intimate – relationship between psychoanalysis and philosophy (specifically ontology) on the basis of the Freudo-Lacanian uncanny and disruptive notions of sexuality and Real.
Alenka Zupanĉiĉ
doaj +1 more source
Advantages and Limitations of Commercially Available Electrocuting Grids for Studying Mosquito Behaviour. [PDF]
Mosquito feeding behaviour plays a major role in determining malaria transmission intensity and the impact of specific prevention measures. Human Landing Catch (HLC) is currently the only method that can directly and consistently measure the biting rates
A Seyoum +49 more
core +4 more sources
Entropy Games and Matrix Multiplication Games [PDF]
Two intimately related new classes of games are introduced and studied: entropy games (EGs) and matrix multiplication games (MMGs). An EG is played on a finite arena by two-and-a-half players: Despot, Tribune and the non-deterministic People.
Asarin, Eugene +5 more
core +4 more sources
Polarization and dispersion properties of elliptical hole golden spiral photonic crystal fiber [PDF]
An elliptical air-hole golden spiral photonic crystal fiber (EGS-PCF) is analyzed with the full-vectorial finite element method. The air-holes in the EGS-PCF are arranged in a spiral pattern governed by the Golden Ratio, where the design has been ...
A. Agrawal +14 more
core +1 more source
The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé +14 more
core +1 more source
Towards a resolved Kennicutt-Schmidt law at high redshift [PDF]
Massive galaxies in the distant Universe form stars at much higher rates than today. Although direct resolution of the star forming regions of these galaxies is still a challenge, recent molecular gas observations at the IRAM Plateau de Bure ...
Bolatto, A. +18 more
core +7 more sources
Iterative Synthesis of Pentacene Derivatives with Continuous Boron–Oxygen Bonds
An iterative synthetic strategy enables the controlled introduction of continuous multiple B–O bonds at the zigzag edge of acenes. A simple two‐step cycle—ipso iodination and Suzuki cross‐coupling/condensation—efficiently constructs BO‐acenes ranging from naphthalene to pentacene.
Seonghwa Jeong +8 more
wiley +2 more sources
Background A method for inhibiting the expression of particular genes using external guide sequences (EGSs) has been developed in bacteria, mammalian cells and maize cells.
Yin Changxin +5 more
doaj +1 more source

