Results 71 to 80 of about 396 (108)

Peripheral immune responses to filoviruses in a reservoir versus spillover hosts reveal transcriptional correlates of disease

Frontiers in Immunology
Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no overt illness upon natural or ...
Jonathan C. Guito, Catherine E. Arnold, Catherine E. Arnold, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, Jessica R. Spengler, Jessica R. Harmon, Joann D. Coleman-McCray, Mariano Sanchez-Lockhart, Gustavo F. Palacios, Jonathan S. Towner, Joseph B. Prescott, Joseph B. Prescott   +13 more
doaj   +1 more source

The latest advancements in Sosuga virus (SOSV) research

Frontiers in Microbiology
The last 60 years have seen the emergence of several zoonotic viruses, some of which originate from bats. Among these are Nipah virus, Marburg virus and Ebola viruses, which have high case fatality rates, and pose significant public health risks. In 2012,
Nathan M. Markarian, Levon Abrahamyan
doaj   +1 more source

Coordinated inflammatory responses dictate Marburg virus control by reservoir bats

Nature Communications
Bats are increasingly recognized as reservoirs of emerging zoonotic pathogens. Egyptian rousette bats (ERBs) are the known reservoir of Marburg virus (MARV), a filovirus that causes deadly Marburg virus disease (MVD) in humans.
Jonathan C. Guito, Shannon G. M. Kirejczyk, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, James Graziano, Jessica R. Spengler, Jessica R. Harmon, David M. Wozniak, Joseph B. Prescott, Jonathan S. Towner   +10 more
doaj   +1 more source

Behavioral risk assessment of exposure to wild and domestic animals in response to a Marburg virus disease outbreak, Ghana 2022

One Health
In July 2022, Ghana reported its first outbreak of Marburg virus disease (MVD). The source of the outbreak was unknown. In August 2022 we conducted a behavioral risk assessment, surveying 715 participants in three rural communities associated with the ...
Richard Suu-Ire, Shannon Ball, Meyir Yiryele Ziekah, Jean DeMarco, Morgan Kain, Amos Sarpong Agyei, Jonathan H. Epstein   +6 more
doaj   +1 more source

Modeling natural coinfection in a bat reservoir shows modulation of Marburg virus shedding and spillover potential.

PLoS Pathogens
The Egyptian rousette bat (ERB) is a natural reservoir for Marburg virus (MARV; family Filoviridae), a putative reservoir for Sosuga virus (SOSV; family Paramyxoviridae), and a vertebrate reservoir for Kasokero virus (KASV; family Orthonairoviridae ...
Amy J Schuh, Brian R Amman, Jonathan C Guito, James C Graziano, Tara K Sealy, Jonathan S Towner   +5 more
doaj   +1 more source

Histologic atlas of the Egyptian rousette (Rousettus aegyptiacus) with an integrated review of macroscopic anatomy. [PDF]

Vet Res
Elbert JA, Amman BR, Sealy TK, Atimnedi P, Towner JS, Howerth EW.   +5 more
europepmc   +1 more source

Atlas of gross, histologic, and immunohistologic anatomy of the lymphoid system in Egyptian rousettes (Rousettus aegyptiacus). [PDF]

Vet Res
Elbert JA, Amman BR, Sealy TK, Atimnedi P, Towner JS, Howerth EW.   +5 more
europepmc   +1 more source

An ordinary differential equation-based integrated pharmacokinetic-pharmacodynamic model for predicting anticoagulant responses to warfarin and diphacinone across rodent and bat species. [PDF]

J Vet Med Sci
Fukamatsu M, Miyamae M, Kamata R, Takeda K.   +3 more
europepmc   +1 more source

Characterization of spontaneous gross and histologic findings in free-ranging Egyptian rousettes (Rousettus aegyptiacus) from Uganda with a review of reported pathogens. [PDF]

Vet Res
Elbert JA, Amman BR, Sealy TK, Atimnedi P, Martin KA, Towner JS, Howerth EW.   +6 more
europepmc   +1 more source

Leveraging organoid models to understand mechanisms of viral infections and immunity in bats. [PDF]

Dis Model Mech
Madden SR, Rynda-Apple A, Bimczok D.
europepmc   +1 more source