Results 31 to 40 of about 1,172,040 (262)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Performance of DF Incremental Relaying with Energy Harvesting Relays in Underlay CRNs

open access: yes, 2017
In this paper, we analyze the throughput performance of incremental relaying using energy harvesting (EH) decode-and-forward (DF) relays in underlay cognitive radio networks (CRNs).
Janghel, Komal, Prakriya, Shankar
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Cytotoxicity and Induction of Inflammation by Pepsin in Acid in Bronchial Epithelial Cells

open access: yesInternational Journal of Inflammation, 2011
Introduction. Gastroesophageal reflux has been associated with chronic inflammatory diseases and may be a cause of airway remodelling. Aspiration of gastric fluids may cause damage to airway epithelial cells, not only because acidity is toxic to ...
Erik Bathoorn   +6 more
doaj   +1 more source

Accurate supercapacitor modeling for energy-harvesting wireless sensor nodes

open access: yes, 2011
Supercapacitors are often used in energy-harvesting wireless sensor nodes (EH-WSNs) to store harvested energy. Until now, research into the use of supercapacitors in EH-WSNs has considered them to be ideal or over-simplified, with non-ideal behavior ...
Al-Hashimi, Bashir   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

On the balanced condition for the Eguchi-Hanson metric

open access: yes, 2018
Let $g_{EH}$ be the Eguchi-Hanson metric on the blow-up of $\mathbb{C}^2$ at the origin. In this paper we show that $mg_{EH}$ is not balanced for any positive integer $m$.Comment: 9 pages, 1 figure, to appear in Journal of Geometry and ...
Aghedu, Francesco Cannas
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Ehe [PDF]

open access: yes
Lexikon nicht-staatlicher Gruppen und Gemeinschaften im Mittelmeerraum ...
  +5 more sources

Conditional UNet emulation of CMAQ simulations for fine particulate matter concentration prediction

open access: yesScientific Reports
Fine particulate matter (PM2.5) pollution poses significant health risks, necessitating accurate predictions for effective management measures for the mitigator of PM2.5.
Yohan Lee   +4 more
doaj   +1 more source

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