Results 81 to 90 of about 1,172,040 (262)
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner +10 more
wiley +1 more source
Predictions of short-term rates and the expectations hypothesis of the term structure of interest rates [PDF]
Despite its important role in monetary policy and finance, the expectations hypothesis (EH) of the term structure of interest rates has received virtually no empirical support.
Guidolin, Massimo, Thornton, Daniel L.
core
Thickness Dependence of Linear and Nonlinear Optical Properties of Multilayer 3R‐MoS2
Thickness as a key design parameter for optimizing the nonlinear optical response of layered transition metal dichalcogenides (TMDs) materials is established. The demonstrated correlation between thickness, linear spectra, and harmonic generation efficiency provides a powerful framework for tailoring nonlinear performance.
Fatemeh Abtahi +6 more
wiley +1 more source
Familial aggregation of first degree relatives of children with essential hypertension
Purpose: Determining familial aggregation is an important first step in narrowing the search for disease-causing genes and hence we determined the familial aggregation of EH among first degree relatives of children with EH.
Monesha Gupta-Malhotra +4 more
doaj +1 more source
Origami‐Inspired Structural Design for Aquatic‐Terrestrial Amphibious Robots
This work presents a lightweight amphibious origami robot actuated by a single shape memory alloy wire. A rigid foldable origami structure with displacement amplification enables efficient terrestrial crawling and aquatic swimming. The addition of fan‐shaped units allows controllable turning in both environments.
Weiqi Liu +5 more
wiley +1 more source
PEP-TP56 enhances AAV transduction in a serotype-independent manner
Adeno-associated viruses (AAVs) have emerged as the most prominent gene therapy vectors. However, the need for high AAV doses to achieve clinical efficacy remains a key challenge to AAV utility in the clinic.
Olaniyi Olarewaju +4 more
doaj +1 more source
A predictive model for 3D printability is developed by integrating rheological analysis, including the Large Amplitude Oscillatory Shear (LAOS) test, with machine learning. With prediction errors under 10%, the model shows that post‐extrusion recovery controls horizontal printability, while high‐strain‐rate nozzle flow dictates vertical printability ...
Eun Hui Jeong +7 more
wiley +1 more source
Extrapleural fat sign is currently regarded as a CT finding that is useful in detecting Extrapleural hematoma (EH). The EH is caused by bleeding between parietal pleura and fascia endothoracica.
Shinjiro Mori +5 more
doaj +1 more source
On the Breakdown of the Ehrenfest Method for Molecular Dynamics on Surfaces
Due to a continuum of electronic states present in periodic systems, the description of molecular dynamics on surfaces poses a serious computational challenge. One of the most used families of approaches in these settings are friction theories, which are
Izmaylov, Artur F., Loaiza, Ignacio
core
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding +5 more
wiley +1 more source

