Results 51 to 60 of about 8,967 (176)

Enterohemorrhagic Escherichia coli induce attaching and effacing lesions and hemorrhagic colitis in human and bovine intestinal xenograft models

open access: yesDisease Models & Mechanisms, 2011
SUMMARY Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important cause of diarrhea, hemorrhagic colitis and hemolytic uremic syndrome in humans worldwide.
Lilach Golan   +4 more
doaj   +1 more source

EHEC Genomics: Past, Present, and Future

open access: yesMicrobiology Spectrum, 2014
ABSTRACT This article examines the role of genomics in the understanding and identification of O157:H7 enterohemorrhagic Escherichia coli (EHEC). We highlight the development of novel molecular typing systems that are based on the genomic sequence that has been generated for this pathotype.
Shah M, Sadiq   +3 more
openaire   +2 more sources

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

open access: yesChemistry – A European Journal, Volume 32, Issue 25, 2 July 2026.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar   +13 more
wiley   +1 more source

Genomic diversity of pathogenic Escherichia coli of the EHEC 2 clonal complex

open access: yesBMC Genomics, 2009
Background Evolutionary analyses of enterohemorrhagic Escherichia coli (EHEC) have identified two distantly related clonal groups: EHEC 1, including serotype O157:H7 and its inferred ancestor O55:H7; and EHEC 2, comprised of several serogroups (O26, O111,
Qi Weihong   +4 more
doaj   +1 more source

Enterohemorrhagic Escherichia coli as causes of hemolytic uremic syndrome in the Czech Republic. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Enterohemorrhagic Escherichia coli (EHEC) cause diarrhea-associated hemolytic uremic syndrome (D+ HUS) worldwide, but no systematic study of EHEC as the causative agents of HUS was performed in the Czech Republic.
Monika Marejková   +4 more
doaj   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

Enhanced actin pedestal formation by enterohemorrhagic Escherichia coli O157:H7 adapted to the mammalian host.

open access: yesFrontiers in Microbiology, 2011
Upon intestinal colonization, enterohemorrhagic Escherichia coli (EHEC) induces epithelial cells to generate actin pedestals beneath bound bacteria, lesions that promote colonization.
Michael John Brady   +8 more
doaj   +1 more source

THE EFFECIENCY OF ENTERIC LACTOBACILLUS IN PREVENTING HEMORRHAGIC COLITIS AND BLOCKING SHIGA TOXINS PRODUCTIONS IN RATS MODELS INFECTED WITH ENTEROHEMORRHAGIC ESCHERICHIA COLI (EHEC)

open access: yesThe Iraqi Journal of Agricultural science, 2021
The objective of this study was to investigate the prophylactic roles of human enteric derived Lactobacillus plantarum L1 (Ll) and Lactobacillus paracasei L2 (L2), on EHEC O157:H7 infection in rodent models (In vivo).
SH. A. Al wendawi, S. M. Al Rekaby
doaj   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

open access: yesInterdisciplinary Medicine, Volume 4, Issue 4, July 2026.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang   +7 more
wiley   +1 more source

A Review on Ecoli 0157: H7 (EHEC)

open access: yesInternational Journal of Scientific Research and Management (IJSRM), 2023
Escherichia coli O157:H7 is an important food borne and water borne pathogen is first isolated in 1982, shiga toxin. producing Ecoli O157:H7 which causes diarrhea, hemorrhagic colitis and haemolytic uremic Syndrome in humans. Haemolytic uremic. Syndrome (Hus) is a Serious condition and upto 50% of Hus patients can develop renal acute dysfunction or ...
S. Meghana, P. Swetha, K. Kalyani
openaire   +1 more source

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