Results 51 to 60 of about 13,614 (218)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Toimenpideohje EHEC-tartuntojen ehkäisemiseksi [PDF]

, 2012
Tämä ohje antaa tietoa toimenpiteistä, joilla voidaan ehkäistä enterohemorraagisen Escherichia coli (EHEC) bakteerin leviämistä tartunnan saaneista henkilöistä. Tavoitteena on yhdenmukaistaa terveydenhuollon toimenpidekäytäntöjä.
Ruutu, Petri, Kuusi, Markku, Jalava, Katri, Siitonen, Anja   +3 more
core  

TccP2 of O157:H7 and non-O157 enterohemorrhagic Escherichia coli (EHEC): challenging the dogma of EHEC-induced actin polymerization [PDF]

, 2007
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 and enteropathogenic E. coli (EPEC) trigger actin polymerization at the site of bacterial adhesion by inducing different signaling pathways. Actin assembly by EPEC requires tyrosine phosphorylation of Tir,
Tennant,S., Tobe,T., Whale,A., Morabito,S., Caprioli,A., Rivas,M., Ogura,Y., Tozzoli,R., Abe,H., Garmendia,J., Robins-Browne,R., Hayashi,T., Ooka,T., Chinen,I., Krause,G., Frankel,G.   +15 more
core   +1 more source

Optimizing the Protection of Cattle against Escherichia coli O157:H7 Colonization through Immunization with Different Combinations of H7 Flagellin, Tir, Intimin-531 or EspA.

PLoS ONE, 2015
Enterohemorrhagic Escherichia coli (EHEC) are important human pathogens, causing hemorrhagic colitis and hemolytic uraemic syndrome in humans. E. coli O157:H7 is the most common serotype associated with EHEC infections worldwide, although other non-O157 ...
Tom N McNeilly, Mairi C Mitchell, Alexander Corbishley, Mintu Nath, Hannah Simmonds, Sean P McAteer, Arvind Mahajan, J Christopher Low, David G E Smith, John F Huntley, David L Gally   +10 more
doaj   +1 more source

THE EFFECIENCY OF ENTERIC LACTOBACILLUS IN PREVENTING HEMORRHAGIC COLITIS AND BLOCKING SHIGA TOXINS PRODUCTIONS IN RATS MODELS INFECTED WITH ENTEROHEMORRHAGIC ESCHERICHIA COLI (EHEC)

The Iraqi Journal of Agricultural science, 2021
The objective of this study was to investigate the prophylactic roles of human enteric derived Lactobacillus plantarum L1 (Ll) and Lactobacillus paracasei L2 (L2), on EHEC O157:H7 infection in rodent models (In vivo).
SH. A. Al wendawi, S. M. Al Rekaby
doaj   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1β in human macrophages and EHEC-induced IL-1β required activation of NLRP3 inflammasome. [PDF]

PLoS ONE, 2012
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a major foodborne pathogen causing hemorrhagic colitis and hemolytic-uremic syndrome. The role of EHEC O157:H7-enterohemolysin (Ehx) in the pathogenesis of infections remains poorly defined.
Xiaoai Zhang, Yuli Cheng, Yanwen Xiong, Changyun Ye, Han Zheng, Hui Sun, Hongqing Zhao, Zhihong Ren, Jianguo Xu   +8 more
doaj   +1 more source

Genomic epidemiology and lineage‐specific risk stratification of tet(X4)‐mediated tigecycline resistance along the pork production chain: A One Health perspective

iMetaOmics, Volume 3, Issue 2, June 2026.
Genome surveillance across a swine‐associated One Health continuum in China shows that slaughterhouses act as major enrichment nodes for tet(X4)‐mediated tigecycline resistance, driven by putative clonal transmission and stable plasmid backbones. Integrating global datasets enables lineage‐specific risk stratification, highlighting key control points ...
Qin Wang, Qiwu Yuan, Xuan Chen, Yujing Zhong, Ke Wu, Renqiao Wen, Luya Liu, Xiaoqin Wang, Cui Li, Hongning Wang, Changwei Lei   +10 more
wiley   +1 more source

Associação de micelas mistas de dodecanoato de Sódio (sdod) e o sal biliar deoxicolato de sódio (nadc) Com uma celulose hidrofobicamente modificada [PDF]

, 2006
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Neste trabalho foram analisadas misturas de deoxicolato de sódio (NaDC) e dodecanoato de sódio (SDoD) em solução tampão de 0,02 M de ...
MODOLON, Samuel de Medeiros
core  

Transcriptomic analysis reveals specific metabolic pathways of enterohemorrhagic Escherichia coli O157:H7 in bovine digestive contents

BMC Genomics, 2018
Background The cattle gastrointestinal tract (GIT) is the main enterohemorrhagic Escherichia coli (EHEC) reservoir. In order to identify nutrients required for the survival or multiplication of EHEC in the bovine GIT, we compared the transcriptomes of ...
Audrey Segura, Marine Bertoni, Pauline Auffret, Christophe Klopp, Olivier Bouchez, Clémence Genthon, Alexandra Durand, Yolande Bertin, Evelyne Forano   +8 more
doaj   +1 more source