Results 201 to 210 of about 168,531 (277)

Expanding Access to Genome Sequencing: Higher Diagnostic Yield in Self‐Referred Participants From the CincyKidsSeq Study and Implications for Hybrid Models of Genetic Service Delivery

Clinical Genetics, EarlyView.
Genome sequencing helped find answers for 1 in 5 children with rare conditions in an outpatient study looking at hybrid genetic care delivery. Families who chose testing themselves had the highest diagnostic yield, showing that self‐referral may be a helpful way to improve access to genetic care.
Kristin Theobald, Amelle Shillington, Farrah Jackson, Jaime Lopes, Casey J. Brewer, Brian Dawson, Gang Wu, James Denton, Mike Pauciulo, Xue Zhang, Anne Slavotinek   +10 more
wiley   +1 more source

Replication of COPD susceptibility loci in a large Chinese elderly population using a validated, multi-setting EHR phenotype. [PDF]

BMC Pulm Med
Pan H, Wu P, Sun K, Xie Z, Qiu Z, Zhang Q, Tian Z, Hou X, Gao S, Chen Y, Zhou X, Cheng Y, Shao J, Wu B, Li Q, Dong W, Peng A, Du Y, Pan Y, Zhou K, Xie T.   +20 more
europepmc   +1 more source

A bio‐ecological model for early screening of developmental coordination disorder

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70069 Abstract Aim To develop and externally validate a bio‐ecological model for early screening of developmental coordination disorder (DCD) using maternal and environmental risk factors from electronic health records, aimed at improving early detection in children under 5 years.
Xiaotian Dai, Tai Ren, Gareth Williams, Gary Jones, Fei Li, Wenchong Du, Jing Hua   +6 more
wiley   +1 more source

Comparison of cardiovascular outcomes between once‐weekly semaglutide and dulaglutide in adults with type 2 diabetes and established atherosclerotic cardiovascular disease in the United States

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This study aims to compare the risk of major adverse cardiovascular events (MACE) among United States individuals with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD) treated with once‐weekly semaglutide vs. dulaglutide.
Xi Tan, Yuanjie Liang, Lin Xie, Joanna Harton, Cynthia Gutierrez, Chalak Muhammad, Caroline Swift, Adam de Havenon   +7 more
wiley   +1 more source

Observer: creation of a novel multimodal dataset for outpatient care research. [PDF]

J Am Med Inform Assoc
Johnson KB, Alasaly B, Jang KJ, Eaton E, Mopidevi S, Koppel R.   +5 more
europepmc   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Meeting the challenges of electronic health record (EHR) optimization. [PDF]

NPJ Digit Med
Makhni S, Cerrato P, Rico J, Niazi S, O'Horo J, Peters S, Shah V, Halamka J.   +7 more
europepmc   +1 more source

An oral glucose tolerance test in pregnancy and its association with future cardiovascular diseases

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims/hypothesis Gestational diabetes and abnormal 100‐g oral glucose tolerance test (OGTT) results in pregnancy are associated with type 2 diabetes, but their relationship with cardiovascular disease (CVD) is less clear. We evaluated the risk of CVD according to the number of abnormal OGTT values during pregnancy.
Tal Schiller, Linoy Gabay, Oren Barak, Alena Kirzhner, Haitham Abu Khadija, Gabriel Chodick, Edi Vaisbuch, Yael Barer   +7 more
wiley   +1 more source

Comparing three natural language processing methods for the automatic identification of epilepsy patients from French clinical notes

Epilepsia, EarlyView.
Abstract Objective Manual review of clinical notes by experts remains the reference standard for identifying patients with epilepsy in health databases. However, this process is labor‐intensive and time‐consuming due to the unstructured nature of text. Prior studies have shown the potential of natural language processing for automated phenotyping.
François Le Gac, Quentin Calonge, Candice Estellat, Vincent Navarro   +3 more
wiley   +1 more source

Maintaining Growth Hormone Therapy Adherence During Shortages: The Role of Specialty Pharmacy. [PDF]

J Pharm Technol
MacDougall J, Cournoyer H.
europepmc   +1 more source