Comprehensive Serology Based on a Peptide ELISA to Assess the Prevalence of Closely Related Equine Herpesviruses in Zoo and Wild Animals. [PDF]
PLoS ONE, 2015 Equine herpesvirus type 1 (EHV-1) causes respiratory disorders and abortion in equids while EHV-1 regularly causes equine herpesvirus myeloencephalopathy (EHM), a stroke-like syndrome following endothelial cell infection in horses.
Azza Abdelgawad +10 more
doaj +12 more sources
Seroprevalence of Equine Herpesvirus 1 (EHV-1) and Equine Herpesvirus 4 (EHV-4) in the Northern Moroccan Horse Populations [PDF]
Animals, 2021 This study reports the first equine herpesvirus-1 (EHV-1) and equine herpesvirus-4 (EHV-4) seroprevalence investigation in horse populations of Morocco in 24 years.
Zineb El Brini +9 more
doaj +2 more sources
The Role of the Equine Herpesvirus Type 1 (EHV-1) US3-Encoded Protein Kinase in Actin Reorganization and Nuclear Egress [PDF]
Viruses, 2016 The serine-threonine protein kinase encoded by US3 gene (pUS3) of alphaherpesviruses was shown to modulate actin reorganization, cell-to-cell spread, and virus egress in a number of virus species.
Alexandra Proft +5 more
doaj +7 more sources
First Molecular and Phylogenetic Characterization of Equine Herpesvirus-1 (EHV-1) and Equine Herpesvirus-4 (EHV-4) in Morocco [PDF]
AnimalsThis study aimed to investigate the molecular prevalence and genetic characterization of EHV-1 and EHV-4 in equid populations in Morocco. A total of 154 equids (114 horses, 9 donkeys, and 31 mules) were sampled, with nasal swabs and tissue samples ...
Zineb El Brini +9 more
doaj +2 more sources
The role of glycoprotein H of equine herpesviruses 1 and 4 (EHV-1 and EHV-4) in cellular host range and integrin binding [PDF]
Veterinary Research, 2012 Equine herpesvirus type 1 and 4 (EHV-1 and EHV-4) glycoprotein H (gH) has been hypothesized to play a role in direct fusion of the virus envelope with cellular membranes.
Azab Walid +2 more
doaj +4 more sources
Detection of equid herpesviruses among different Arabian horse populations in Egypt [PDF]
Veterinary Medicine and Science, 2019 Equid herpesviruses (EHVs) threaten equine health and can cause significant economic losses to the equine industry worldwide. Different equid herpesviruses, EHV‐1, EHV‐2, EHV‐4 and EHV5 are regularly detected among horse populations. In Egypt, monitoring
Walid Azab +8 more
doaj +2 more sources
Equid Alphaherpesvirus 1 (EHV-1) Influences Morphology and Function of Neuronal Mitochondria In Vitro [PDF]
Pathogens, 2022 Mitochondria are key cellular organelles responsible for many essential functions, including ATP production, ion homeostasis and apoptosis induction. Recent studies indicate their significant role during viral infection. In the present study, we examined
Marcin Chodkowski +7 more
doaj +2 more sources
Investigation of an EHV-1 Outbreak in the United States Caused by a New H752 Genotype [PDF]
Pathogens, 2021 Here we report on an EHV-1 outbreak investigation caused by a novel genotype H752 (histidine in amino acid position 752 of the ORF 30 gene). The outbreak involved 31 performance horses.
Nicola Pusterla +6 more
doaj +2 more sources
Molecular Monitoring of EHV-1 in Silently Infected Performance Horses through Nasal and Environmental Sample Testing [PDF]
Pathogens, 2022 While the main goal in the management of an EHM outbreak focuses on identifying early clinical disease in order to physically separate infected horses, little effort is placed towards monitoring healthy horses.
Nicola Pusterla +7 more
doaj +2 more sources
Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP. [PDF]
PLoS Pathogens, 2008 Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Danijela Koppers-Lalic +19 more
doaj +6 more sources