Results 81 to 90 of about 85,247 (140)

Tricyclic Pyrrole-Based Compounds as Zika Virus Inhibitors. [PDF]

Int J Mol Sci
Murineddu G, Plicanti E, Corona P, Di Marzo C, Asproni B, Lupinu I, Lottini G, Piras S, Carta A.   +8 more
europepmc   +1 more source

Identification and characterization of novel chikungunya virus polymerase inhibitors. [PDF]

J Virol
Yin P, Boyce R, Wang S, Sirrine M, Leach A, Chu D, Vyshenska D, Sahin Z, Wong J, Moore T, Lewis DSM, Pelly SC, Liotta D, Merits A, Greninger AL, Plemper RK, Kielian M, Cox RM.   +17 more
europepmc   +1 more source

New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors. [PDF]

Pharmaceuticals (Basel)
Obergfäll D, Hahn F, Kicuntod J, Wangen C, Kögler M, Wagner S, Kaufer B, Marschall M.   +7 more
europepmc   +1 more source

Carboxylesterase Factors Influencing the Therapeutic Activity of Common Antiviral Medications Used for SARS-CoV-2 Infection. [PDF]

Pharmaceutics
Shen Y, Eades W, Dinh L, Yan B.
europepmc   +1 more source

A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity. [PDF]

Nat Commun
Tsujino S, Tsuda M, Deguchi S, Ito J, Taha TY, Nasser H, Wang L, Rosecrans J, Suzuki R, Suzuki S, Yoshimatsu K, Ott M, Ikeda T, Sato K, Takayama K, Tanaka S, Tamura T, Fukuhara T, Genotype to Phenotype Japan (G2P-Japan) Consortium.   +18 more
europepmc   +1 more source

Advances in the Treatment of Enterovirus-D68 and Rhinovirus Respiratory Infections. [PDF]

Infect Dis Rep
Rahajamanana VL, Thériault M, Rabezanahary H, Sahnoun YG, Mallet MC, Isabel S, Trottier S, Baz M.   +7 more
europepmc   +1 more source

3-Deazaguanosine inhibits SARS-CoV-2 viral replication and reduces the risk of COVID-19 pneumonia in hamster. [PDF]

iScience
Saito-Tarashima N, Koma T, Hinotani N, Yoshida K, Ogasa M, Murai A, Inoue S, Kondo T, Doi N, Tsuneyama K, Nomaguchi M, Minakawa N.   +11 more
europepmc   +1 more source

Clinical trial of molnupiravir with or without an oral immune stimulant as a first-line treatment of feline infectious peritonitis. [PDF]

J Feline Med Surg
Černá P, Dow S, Hawley J, Willis M, Lappin MR.   +4 more
europepmc   +1 more source

SARS-CoV-2 Error Catastrophe Under Molnupiravir: Mutagenic Enhancement Enables Viral Persistence with Impaired Fitness. [PDF]

Viruses
Tomita Y, Miyazaki K, Mochizuki R, Hasegawa H.   +3 more
europepmc   +1 more source

Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir. [PDF]

Sci Adv
Rakib A, Das A, Bera SC, Cnossen J, Robles-Sikisaka R, Diefenbacher MV, America PPB, Klein M, Anderson TK, Marecki JC, Wang B, Bogers E, Feng JY, Bilello JP, Papini FS, Smitskamp Q, Sheahan TP, Arnold JJ, Routh A, Artsimovitch I, Kirchdoerfer RN, Cameron CE, Raney KD, Dulin D.   +23 more
europepmc   +1 more source