Results 171 to 180 of about 698,026 (317)

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah   +3 more
wiley   +1 more source

Representation of the norming constants by two spectra

open access: yesElectronic Journal of Differential Equations, 2010
The representation of the norming constants by 2 spectra was studied by Levitan, Gasymov (and others) for the Sturm-Liouville problem with boundary conditions $y(0)cosalpha +y'(0)sinalpha=0$, $y(pi)coseta+y'(pi)sineta =0$, when $sin alpha eq 0$ and $
Tigran N. Harutyunyan
doaj  

Robust Reinforcement Learning Control Framework for a Quadrotor Unmanned Aerial Vehicle Using Critic Neural Network

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quadrotor unmanned aerial vehicle control is critical to maintain flight safety and efficiency, especially when facing external disturbances and model uncertainties. This article presents a robust reinforcement learning control scheme to deal with these challenges.
Yu Cai   +3 more
wiley   +1 more source

Riesz bases generated by the spectra of Sturm-Liouville problems

open access: yesElectronic Journal of Differential Equations, 2013
Let ${lambda _n^2} _{n = 0}^infty$ be the spectra of a Sturm-Liouville problem on $[0,pi ]$. We investigate the question: Do the systems ${ cos(lambda_nx)} _{n = 0}^infty$ or ${ sin(lambda_n x)} _{n = 0}^infty$ form Riesz bases in ${L^2}[0,pi ]$? The
Tigran Harutyunyan   +2 more
doaj  

On the second eigenvalue of nonlinear eigenvalue problems

open access: yesElectronic Journal of Differential Equations, 2018
This article is devoted to the characterization of the second eigenvalue of nonlinear eigenvalue problems. We propose an abstract approach which allows to treat nonsmooth quasilinear problems and also to recover, in a unified way, previous results concerning the p-Laplacian.
DEGIOVANNI M., MARZOCCHI M.
openaire   +2 more sources

Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao   +5 more
wiley   +1 more source

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