Results 111 to 120 of about 436,268 (347)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Epicardial adipose tissue (EAT) accumulation is thought to play a role in the pathophysiology of heart failure (HF) with mid‐range ejection fraction and HF with preserved ejection fraction, but its effect on outcome is unknown.
Wenxian Wang +7 more
doaj +1 more source
Comparison of different segmentation approaches without using gold standard. Application to the estimation of the left ventricle ejection fraction from cardiac cine MRI sequences. [PDF]
, 2011 International audienceA statistical method is proposed to compare several estimates of a relevant clinical parameter when no gold standard is available.
Buvat, Irène +16 more
core +3 more sources
B49. CRITICAL CARE: HEMODYNAMICS AND AFFAIRS OF THE HEART, 2020 S. Uppalapu +5 more
openaire +1 more source
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
Advanced Healthcare Materials, EarlyView.This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla +16 more
wiley +1 more source
Visual versus fully automated assessment of left ventricular ejection fraction
Avicenna Journal of Medicine, 2018 Introduction: The aim of this study is to compare three different echocardiographic methods commonly used in the assessment of left ventricle (LV) ejection fraction (EF). Methods: All patients underwent full echocardiography including LVEF assessed using
Rami Mahmood Abazid +10 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho +7 more
wiley +1 more source
SEGUE-2 Limits on Metal-Rich Old-Population Hypervelocity Stars In the Galactic Halo
, 2010 We present new limits on the ejection of metal-rich old-population hypervelocity stars from the Galactic center (GC) as probed by the SEGUE-2 survey.
Abadi +50 more
core +1 more source
Metal Enrichment of the Intergalactic Medium in Cosmological Simulations [PDF]
, 2001 Observations have established that the diffuse intergalactic medium (IGM) at z ~ 3 is enriched to ~0.1-1% solar metallicity and that the hot gas in large clusters of galaxies (ICM) is enriched to 1/3-1/2 solar metallicity at z=0.
Anthony Aguirre +17 more
core +3 more sources
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundClinical benefits from His bundle pacing (HBP) in heart failure patients with preserved and reduced left ventricular ejection fraction are still inconclusive.
Weijian Huang +6 more
doaj +1 more source