Results 241 to 250 of about 2,235,192 (340)
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang +7 more
wiley +1 more source
Renal function trajectories in 'De Novo' heart failure with reduced ejection fraction: impact on outcomes. [PDF]
Otero Garcia O +11 more
europepmc +1 more source
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo +10 more
wiley +1 more source
Mechanical stretch reduces fibroblast activation in heart failure with reduced ejection fraction. [PDF]
Silverman DN +10 more
europepmc +1 more source
Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen +6 more
wiley +1 more source
Homocysteine is a risk factor for reduced ejection fraction in children with myocarditis: a single-center study. [PDF]
Zhang C +6 more
europepmc +1 more source

