Results 311 to 320 of about 2,021,559 (378)

Is ejection fraction a reliable marker of left ventricular contractility? Comparison with emax in chronic animal models with load alterations Yong Jin Kim, Michael Jones, Takahiro Shiota, Fabrice Bauer, Jian Xin Qin, Marta Sitges, Hiroyuki Tsujino, Agnese Travaglini, Lisa A. Cardon, Arthur D. Zetts, Julio A. Panza, James D. Thomas. The Cleveland Clinic Foundation, Cleveland, OH, National Heart, Lung and Blood Institute of Health, Bethesda, MD

, 2001

openalex   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Finerenone in Heart Failure With Improved Ejection Fraction: The FINEARTS-HF Randomized Clinical Trial.

JAMA Cardiol
Pabon MA, Vardeny O, Vaduganathan M, Desai AS, Claggett BL, Kulac IJ, Jhund PS, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Pitt B, Saldarriaga CI, Petrie MC, Merkely B, Borentain M, Mueller K, Viswanathan P, Amarante F, Morris A, McMurray JJV, Solomon SD.   +22 more
europepmc   +1 more source

Coverable Self‐Cleaning Glass via Abnormal Transport and Jump of Charged Particles

Advanced Science, EarlyView.
The abnormal reverse lateral transport behavior of charged particles is reported. The mechanism of transport and jump behaviors of charged particles is revealed. Furthermore, a transparent and simple self‐cleaning glass driven by the electric field is developed.
Meng Yang, Conglin Li, Wei Tang, Wenchao Gao, Weiguo Weng, Yingchun Wu, Yifan Wang, Chenghang Zheng, Xiang Gao   +8 more
wiley   +1 more source

Strategically Constructing Alkali‐Metal Interfacial Bridges to Boost Photocatalytic CO2 Methanation on Supported Ni─Ru Bimetallic Catalysts

Advanced Science, EarlyView.
Strategically anchoring Na at the Ni─Ru/ZrO2 interface creates a robust Ni0─Niδ+─Na─O─Ru electronic bridge, significantly enhancing electron transfer and inter‐metal synergy. This interface accelerates photocatalytic CO2 methanation via stabilized *COOH intermediates and efficient H2 activation, boosting CH4 yield.
Xiaolei Guo, Yuqi Wu, Shengrong Zhou, Yuhang Shao, Yasuo Izumi, Jinlu He, Hongwei Zhang   +6 more
wiley   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, EarlyView.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Bio‐Inspired Stored Magnetic Energy Actuator with Transient Triggering and Programmable Logic

Advanced Science, EarlyView.
A bio‐inspired magnetic energy actuator achieves 1.6 m/s transient release—three orders faster than conventional systems—via direct ink writing printed NdFeB/Polydimethylsiloxane composites and environmental locks; biomimetic AND‐gate logic enables sequential cue recognition (e.g., “temperature → rainfall”).
Chao Xu, Shuo Jiang, Lu Zhang, Xueli Zhou, Qingping Liu, Luquan Ren   +5 more
wiley   +1 more source

Electro‐Thermally Controlled Active Mechanical Metamaterials with Programmable Stiffness and Nonreciprocity

Advanced Science, EarlyView.
Actively programmable mechanical metamaterial, featuring smart conductive polymers, designed instabilities, and compliant mechanisms. Capable of stiffness switching, local surface pressure modulation, and nonreciprocal shear relationships that allow local shielding from surface traction. Potential applications in soft robotic grippers and smart medical
Jai Dunne, Robert D. Crapnell, Krzysztof K. Dudek, Tom Allen, Craig E. Banks, Olly Duncan   +5 more
wiley   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Highly Efficient and Flexible Thin Film Thermoelectric Materials from Blends of PEDOT:PSS and AgSb0.94Cd0.06Te2

Advanced Electronic Materials, EarlyView.
Highly mechanically stable and flexible composite TE thin films based on PEDOT:PSS and AgSb0.94Cd0.06Te2 blend are fabricated. Simultaneous enhancement of S and σ is achieved in the whole blend regime. A very high Seebeck coefficient (204.9 µV K−1) and a power factor of 53.45 µW m−1 K−2 are obtained for 97.5 wt.% AgSb0.94Cd0.06Te2 content.
Mahima Goel, Adrian Hochgesang, Animesh Bhui, Kanishka Biswas, Mukundan Thelakkat   +4 more
wiley   +1 more source