Results 31 to 40 of about 2,021,559 (378)

Heart failure with preserved ejection fraction [PDF]

Pflügers Archiv - European Journal of Physiology, 2014
Heart failure (HF) is a clinical syndrome of diverse etiologies and can be associated with preserved, reduced, or mid-range ejection fraction (EF). In the community, heart failure with preserved ejection fraction (HFpEF) is emerging as the most common form of HF.
Margaret M. Redfield, Wolfgang A. Linke, James D. Gladden   +2 more
openaire   +9 more sources

The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

Nature Network Boston, 2021
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of symptoms and functional limitations, and have a poor quality of life.
M. Nassif, Sheryl L. Windsor, B. Borlaug, D. Kitzman, Sanjiv J. Shah, F. Tang, Yevgeniy Khariton, A. Malik, T. Khumri, G. Umpierrez, S. Lamba, K. Sharma, S. Khan, Lokesh Chandra, R. Gordon, J. Ryan, S. Chaudhry, S. Joseph, C. Chow, M. Kanwar, M. Pursley, E. Siraj, G. Lewis, B. Clemson, Michael W Fong, M. Kosiborod   +25 more
semanticscholar   +1 more source

Heart failure with mid-range or mildly reduced ejection fraction

Nature Reviews Cardiology, 2021
Left ventricular ejection fraction (EF) remains the major parameter for diagnosis, phenotyping, prognosis and treatment decisions in heart failure. The 2016 ESC heart failure guidelines introduced a third EF category for an EF of 40–49%, defined as heart
G. Savarese, D. Stolfo, G. Sinagra, L. Lund   +3 more
semanticscholar   +1 more source

Heart failure with mildly reduced ejection fraction: emerging frontiers in clinical characteristics, prognosis, and treatment [PDF]

Reviews in Cardiovascular Medicine, 2022
Heart failure (HF) is a complex clinical syndrome resulting from the impairment of ventricular filling or ejection of blood or both, leading to considerable morbidity and mortality. Based on left ventricular ejection fraction (LVEF), the 2016 European
Zhi Shang, Xinyu Wang, Wei Gao
doaj   +1 more source

Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

Nature Network Boston, 2022
Whether the sodium–glucose cotransporter 2 inhibitor dapagliflozin reduces the risk of a range of morbidity and mortality outcomes in patients with heart failure regardless of ejection fraction is unknown.
P. Jhund, T. Kondo, J. Butt, K. Docherty, B. Claggett, Akshay S. Desai, M. Vaduganathan, S. Gasparyan, O. Bengtsson, D. Lindholm, Magnus Petersson, A. Langkilde, R. D. de Boer, D. DeMets, A. Hernandez, S. Inzucchi, M. Kosiborod, L. Køber, C. Lam, F. Martinez, M. Sabatine, Sanjiv J. Shah, S. Solomon, J. McMurray   +23 more
semanticscholar   +1 more source

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.

New England Journal of Medicine, 2019
BACKGROUND In patients with type 2 diabetes, inhibitors of sodium-glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms. More data are needed regarding the effects of
J. McMurray, S. Solomon, S. Inzucchi, L. Køber, M. Kosiborod, F. Martinez, P. Ponikowski, M. Sabatine, I. Anand, J. Bělohlávek, M. Böhm, C. Chiang, V. Chopra, Rudolf A. de Boer, Akshay S. Desai, M. Diez, J. Drożdż, A. Dukát, J. Ge, J. Howlett, T. Katova, M. Kitakaze, C. Ljungman, B. Merkely, J. Nicolau, E. O’Meara, M. Petrie, P. N. Vinh, M. Schou, S. Tereshchenko, S. Verma, C. Held, D. DeMets, K. Docherty, P. Jhund, O. Bengtsson, M. Sjöstrand, A. Langkilde, Modele O Ogunniyi   +38 more
semanticscholar   +1 more source

Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.

New England Journal of Medicine, 2020
BACKGROUND The effect of vericiguat, a novel oral soluble guanylate cyclase stimulator, in patients with heart failure and reduced ejection fraction who had recently been hospitalized or had received intravenous diuretic therapy is unclear.
P. Armstrong, B. Pieske, K. Anstrom, J. Ezekowitz, Adrian F. Hernandez, J. Butler, C. Lam, P. Ponikowski, A. Voors, G. Jia, S. McNulty, M. Patel, L. Roessig, J. Koglin, C. O'connor   +14 more
semanticscholar   +1 more source

Diabetes Associated With Greater Ejection Fraction Improvement After Revascularization in Patients With Reduced Ejection Fraction

Frontiers in Cardiovascular Medicine, 2021
Objectives: To investigate the association between diabetes mellitus (DM) and ejection fraction (EF) improvement following revascularization in patients with coronary artery disease (CAD) and left ventricular (LV) dysfunction.Background ...
Shaoping Wang, Shaoping Wang, Bijan J. Borah, Bijan J. Borah, Shujuan Cheng, Shiying Li, Ze Zheng, Xiaoyan Gu, Ming Gong, Yi Lyu, Jinghua Liu   +10 more
doaj   +1 more source

Patiromer for the management of hyperkalemia in heart failure with reduced ejection fraction: the DIAMOND trial

European Heart Journal, 2022
Aims To investigate the impact of patiromer on the serum potassium level and its ability to enable specified target doses of renin–angiotensin–aldosterone system inhibitor (RAASi) use in patients with heart failure and reduced ejection fraction (HFrEF ...
J. Butler, S. Anker, L. Lund, A. Coats, G. Filippatos, T. Siddiqi, T. Friede, V. Fabien, M. Kosiborod, M. Metra, I. Piña, F. Pinto, P. Rossignol, P. van der Meer, Cecilia Bahit, J. Bělohlávek, M. Böhm, J. Brugts, J. Cleland, J. Ezekowitz, A. Bayés‐Genís, I. Gotsman, A. Goudev, I. Khintibidze, J. Lindenfeld, R. Mentz, B. Merkely, Eliodoro Castro Montes, W. Mullens, J. Nicolau, A. Parkhomenko, P. Ponikowski, P. Seferovic, M. Senni, E. Shlyakhto, A. Cohen-Solal, P. Szecsödy, K. Jensen, F. Dorigotti, M. Weir, B. Pitt   +40 more
semanticscholar   +1 more source

The Role of Cardiac Imaging in Heart Failure with Reduced Ejection Fraction

Cardiac Failure Review, 2022
Heart failure (HF) is a major health burden associated with significant morbidity and mortality. Approximately half of all HF patients have reduced ejection fraction (left ventricular ejection fraction
Rebecca C Gosling, Abdallah Al-Mohammad
doaj   +1 more source