Results 31 to 40 of about 1,079,877 (255)

Phenotyping Heart Failure According to the Longitudinal Ejection Fraction Change: Myocardial Strain, Predictors, and Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Many patients with heart failure (HF) experience changes in left ventricular ejection fraction (LVEF) during follow‐up. We sought to evaluate the predictors and outcomes of different HF phenotypes according to longitudinal changes in EF ...
Jin Joo Park, Alexandre Mebazaa, In‐Chang Hwang, Jun‐Bean Park, Jae‐Hyeong Park, Goo‐Yeong Cho   +5 more
doaj   +1 more source

The Prognostic Role of the Left Atrium in Hypertensive Patients with HFpEF: Does Function Matter More than Structure?

Life
Background: In arterial hypertension (AH), adverse hemodynamic consequences in the left atrium (LA) are often observed. The prognostic significance of functional vs.
Artem Ovchinnikov, Alexandra Potekhina, Anastasiia Filatova, Olga Svirida, Maria Sobolevskaya, Alfiya Safiullina, Fail Ageev   +6 more
doaj   +1 more source

Surgical myocardial revascularization of patients with ischemic cardiomyopathy and severe left ventricular disfunction

Clinics, 2010
OBJECTIVE: To determine long-term survival, identify preoperative factors predictive of a favorable outcome, and assess functional improvement after coronary artery bypass grafting in patients with advanced left ventricular dysfunction.
André L. Hovnanian, Alexandre de Matos Soeiro, Carlos Vicente Serrano Jr, Sérgio Almeida de Oliveira, Fábio B. Jatene, Noedir A. G. Stolf, José A. F. Ramires   +6 more
doaj   +1 more source

Sodium-Glucose Co-transporter-2 Inhibitors in Heart Failure with Preserved Ejection Fraction: A Breakthrough in Improvement of Clinical Outcomes?

, 2022
The conventional conception of the therapy of heart failure (HF) with reduced ejection fraction has been recently modified by adding sodium-glucose co-transporter-2 (SGLT2) inhibitors to the combination consisting of beta blockers, mineralocorticoid ...
Alexander A. Berezin, Alexander E. Berezin   +1 more
core   +1 more source

The DNA Ejection Process in Bacteriophage λ [PDF]

, 2007
Bacteriophages have long served as model systems through which the nature of life may be explored. From a physical or mechanical point of view, phages are excellent examples of natural nanotechnology: they are nanometer-scale systems which depend ...
Grayson, Paul Daniel
core   +1 more source

Effects of statins on functional capacity and cardiac remodeling in patients with heart failure and preserved ejection fraction: a randomized open-label pilot trial

Frontiers in Cardiovascular Medicine
BackgroundSystemic inflammation is an essential pathophysiological factor of heart failure with preserved ejection fraction (HFpEF) that supports the use of statins.
Artem Ovchinnikov, Artem Ovchinnikov, Alexandra Potekhina, Olga Svirida, Tatiana Arefieva, Tamila Martynyuk, Fail Ageev, Marijana Tadic, Evgeny Belyavskiy   +8 more
doaj   +1 more source

Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload [PDF]

, 2010
Aim: We aimed to define reference ranges for right ventricular (RV) volumes, ejection fraction (EF) in thalassemia major patients (TM) without myocardial iron overload.Methods and results: RV volumes, EF and mass were measured in 80 TM patients who had ...
Maciej Garbowski, He, TG, Maceira, A, Francisco Alpendurada, Banya Winston, He, T, Taigang He, Carpenter, JP, Smith, GC, Kirk, P, Shah, F, Maceira Alicia, Porter, JB, John B Porter, Banya, W, He Taigang, Walker, JM, Kirk Paul, Alicia Maceira, Alpendurada Francisco, Gillian C Smith, Porter John B, Smith Gillian C, Farrukh Shah, Pennell, DJ, Shah Farrukh, Pennell Dudley J, Deac Monica, Dudley J Pennell, Alpendurada, F, Paul Kirk, Winston Banya, Carpenter John-Paul, John-Paul Carpenter, Deac, M, J Malcolm Walker, Garbowski, M, Walker J Malcolm, Garbowski Maciej, Monica Deac   +39 more
core   +1 more source

Effects of empagliflozin on functional capacity, LV filling pressure, and cardiac reserves in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction: a randomized controlled open-label trial

Cardiovascular Diabetology
Background Clinical trials have established the prognostic benefits of sodium‒glucose cotransporter 2 (SGLT2) inhibitors in patients with type 2 diabetes mellitus (T2DM) and heart failure (HF) with preserved ejection fraction (HFpEF), although the ...
Artem Ovchinnikov, Alexandra Potekhina, Anastasiia Filatova, Olga Svirida, Kristina Zherebchikova, Fail Ageev, Evgeny Belyavskiy   +6 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Pharmacological management of heart failure with reduced ejection fraction

, 2022
Heart failure with reduced ejection fraction is a disease with a high prevalence, cost, and mortality rate. However, in recent years, new diagnostic and management breakthroughs have been made, as well as new pharmacological and non-pharmacological ...
Oladunjoye, Kayode
core