Results 11 to 20 of about 120 (95)
Structural insights into regulation of CCN protein activities and functions. [PDF]
Graphical abstract Suggested mechanism for activation and inhibition of signaling by the CCN protein family (graphics generated with BioRender.com). Abstract CCN proteins play important functions during development, in repair mechanisms following tissue injury, as well as in pathophysiologic mechanisms of metastasis of cancer.
Monsen VT, Attramadal H.
europepmc +2 more sources
Abstract In the first year of life, infants' speech perception becomes attuned to the sounds of their native language. This process of early phonetic learning has traditionally been framed as phonetic category acquisition. However, recent studies have hypothesized that the attunement may instead reflect a perceptual space learning process that does not
Yevgen Matusevych +4 more
wiley +1 more source
Graphical abstract Abstract The cellular (centralized) communication network (CCN) factor protein family contains six small secreted cysteine‐rich proteins sharing high structural similarity. These matricellular proteins have vital biological functions in cell adhesion, migration, cell cycle progression, and control of production and degradation of ...
Erawan Borkham‐Kamphorst +2 more
wiley +1 more source
Before perceptual narrowing: The emergence of the native sounds of language
Abstract The present study investigates the precursors of representations of phonemes in 4.5‐month‐olds. The emergence of phonemes has been mainly studied within the framework of perceptual narrowing, that is, infants tuning to their native language and losing sensitivity to non‐native speech.
Konstantina Zacharaki +1 more
wiley +1 more source
A matrix therapy agent marketed as CACIPLIQ20® showed marked improvement in the healing rate of hand infections, including functional recovery. It can be used at both earlier and later stages to promote faster healing and prevent an adverse outcome. Abstract A matrix therapy agent marketed as CACIPLIQ20® showed marked improvement in the healing rate of
Sharifah Ahmad Roohi +2 more
wiley +1 more source
United European Gastroenterology Journal, Volume 5, Issue S5, Page A837-A875, October 2017.
europepmc +2 more sources
CCN5/WISP2 and metabolic diseases
Abstract Obesity and type 2 diabetes increase worldwide at an epidemic rate. It is expected that by the year 2030 around 500 million people will have diabetes; predominantly type 2 diabetes. The CCN family of proteins has become of interest in both metabolic and other common human diseases because of their effects on mesenchymal stem cell (MSCs ...
John R Grünberg +5 more
wiley +1 more source
Abstract The CCN family of proteins typically consists of four distinct peptide domains: an insulin‐like growth factor binding protein‐type (IGFBP) domain, a Von Willebrand Factor C (VWC) domain, a thrombospondin type 1 repeat (TSP1) domain, and a carboxy‐terminal (CT) domain.
Lan Wei +4 more
wiley +1 more source
Abstract The six proteins of the CCN family have important roles in development, angiogenesis, cell motility, proliferation, and other fundamental cell processes. To date, CCN5 distribution in developing rodents and humans has not been mapped comprehensively. CCN5 strongly inhibits adult smooth muscle cell proliferation and motility.
Jennifer A. Jones +4 more
wiley +1 more source
CCN5 Expression in mammals. II. Adult rodent tissues
Abstract CCN5 is a secreted heparin‐ and estrogen‐regulated matricellular protein that inhibits vertebrate smooth muscle cell proliferation and motility. CCN5 is expressed throughout murine embryonic development in most organs and tissues. However, after embryonic development is complete, we hypothesized that CCN5 distribution would be largely ...
Mark R. Gray +4 more
wiley +1 more source

