Results 51 to 60 of about 6,233,754 (256)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Analysis of Natural Frequencies of a MacPherson Suspension Using Different Bushings’ Elastic Characteristics

Engineering Proceedings
The first natural frequency is the most important vibration parameter during the design of suspensions. It has a major impact on vehicle ride comfort and handling.
Stiliyana Taneva, Krasimir Ambarev, Valyo Nikolov   +2 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

First-principles analysis of X2InBiF6 (X = Na, K and Rb) fluoroperovskites for optoelectronic and photovoltaic applications

Next Materials
This study investigates the potential of fluoroperovskite compounds X2InBiF6, where X represents sodium, potassium, or rubidium, for renewable energy applications.
Abdelghafour El Mekkaouy, El Houcine Akarchaou, Samir Chtita, Ahmed Sali, Hassan Khajmi, Rodouan Touti   +5 more
doaj   +1 more source

A new criterion of coal burst proneness based on the residual elastic energy index

International Journal of Mining Science and Technology, 2021
To evaluate the coal burst proneness more precisely, a new energy criterion namely the residual elastic energy index was proposed. This study begins by performing the single-cyclic loading-unloading uniaxial compression tests with five pre-peak unloading
Fengqiang Gong, Yunliang Wang, Zhiguo Wang, Junfeng Pan, Song Luo   +4 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Elastic-Net forecasts.

, 2023
Elastic-Net forecasts for all 4 test seasons (2015/16 to 2018/19) and forecasting horizons (γ = 7, 14, 21, and 28). The influenza-like illness (ILI) rate (ground truth) is shown by the black line. (EPS)
Ingemar J. Cox (16892341), Peter Hayes (10433), Vasileios Lampos (392161), Michael Morris (1820158)   +3 more
core   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Convergence of equilibria of thin elastic plates under physical growth conditions for the energy density [PDF]

, 2012
The asymptotic behaviour of the equilibrium configurations of a thin elastic plate is studied, as the thickness of the plate goes to zero. More precisely, it is shown that critical points of the nonlinear elastic functional converge to critical points of
Maria Giovanna Mora, Lucia Scardia, Davoli, E., Scardia, L., Mora, M.G., Mora, M. G.   +5 more
core   +1 more source

A New Correlation for Estimating Static Elastic Properties of Sandstone Formations: Case Study from Rumaila Oilfield

Iraqi Geological Journal
Evaluating the elastic characteristics of reservoir's rocks is crucial for the oil and gas sector to reduce risks throughout drilling and production operations. Elastic parameters are essential for prediction of wellbore stability, estimation of
Doaa Mahdi, Ayad Alrazzaq
doaj   +1 more source