Results 51 to 60 of about 5,746,922 (239)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

A new criterion of coal burst proneness based on the residual elastic energy index

International Journal of Mining Science and Technology, 2021
To evaluate the coal burst proneness more precisely, a new energy criterion namely the residual elastic energy index was proposed. This study begins by performing the single-cyclic loading-unloading uniaxial compression tests with five pre-peak unloading
Fengqiang Gong, Yunliang Wang, Zhiguo Wang, Junfeng Pan, Song Luo   +4 more
doaj   +1 more source

Elastic-crack model.

, 2022
Elastic-crack model.
Zuguo Mo (14019691), Enlong Liu (14019700), Fujun Xue (14019697), Jianhai Zhang (3418490), Tianzhi Yao (14019694), Li Qian (36199), Ru Zhang (431993), Yunpeng Gao (5205260)   +7 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

First-principles analysis of X2InBiF6 (X = Na, K and Rb) fluoroperovskites for optoelectronic and photovoltaic applications

Next Materials
This study investigates the potential of fluoroperovskite compounds X2InBiF6, where X represents sodium, potassium, or rubidium, for renewable energy applications.
Abdelghafour El Mekkaouy, El Houcine Akarchaou, Samir Chtita, Ahmed Sali, Hassan Khajmi, Rodouan Touti   +5 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Research on the Elastic Loss Characteristics of Acoustic Echoes from Underwater Corner Reflector

Sensors
The underwater corner reflector is a “concave” elastic structure, and its acoustic echo exhibits large elastic loss, which affects its practical use. To study the acoustic echo elastic loss characteristics of underwater corner reflectors, based on the ...
Yi Luo, Dawei Xiao, Jingzhuo Zhang, Zuqiu Li   +3 more
doaj   +1 more source

Analysis on the fluid-structure interaction vibration characteristics of the elastic propeller

Zhongguo Jianchuan Yanjiu, 2020
[Objectives] In the flow field, vibration response characteristics of the elastic propeller are influenced by the interaction of the fluid and structure.[Methods] Based on the CFD/FEM fluid-structure interaction method,ANSYS-CFX modules on the Workbench ...
TAN Yuhang, PENG Weicai
doaj   +1 more source

Hardness Results on Characteristics for Elastic-Degenerated Strings

CoRR
Generalizations of plain strings have been proposed as a compact way to represent a collection of nearly identical sequences or to express uncertainty at specific text positions by enumerating all possibilities. While a plain string stores a character at each of its positions, generalizations consider a set of characters (indeterminate strings), a set ...
Köppl, Dominik, Olbrich, Jannik
openaire   +3 more sources