Results 31 to 40 of about 1,691,427 (247)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Diffusion law and diffusion model for backfill grouting in loess shield tunnel at different soil moisture

Underground Space
Loess is a special type of soil whose properties are significantly affected by water. However, the grout diffusion law for backfill grouting in loess shield tunnels remains unknown.
Sihan Li, Fei Ye, Caifei Zhang, Yong Yang, Tianhan Xia, Yin Jiang, Xingbo Han   +6 more
doaj   +1 more source

Diffuso-Kinetics and Diffuso-Mechanics of Carbon Dioxide / Polyvinylidene Fluoride System under Explosive Gas Decompression: Identification of Key Diffuso-Elastic Couplings by Numerical and Experimental Confrontation

Oil & Gas Science and Technology, 2015
The work aims at identifying the key diffuso-elastic couplings which characterize a numerical tool developed to simulate the irreversible ‘Explosive Decompression Failure’ (XDF) in semi-crystalline polymer.
Grandidier Jean-Claude, Baudet Cédric, Boyer Séverine A.E., Klopffer Marie-Hélène, Cangémi Laurent   +4 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Molecular diffusion under confinement [PDF]

, 2005
With reference to molecular transport in manifold media of porous structure, a survey is given on the ample spectrum of diffusion phenomena under confinement.
Kärger, Jörg
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

The Effect of Diffuseness Parameter on the Quasi-Elastic Scattering of the 25Mg + 90Zr and 28Si + (120Sn ,150Nd) Systems using Wood-Saxon Potential

East European Journal of Physics, 2023
      In this research, the effect of changing the values of the diffusion parameter on the semi-elastic scattering ( ) and distribution (D) calculations for (SC) and (CC) have been studied.
Khalid S. Jassim, Farah J. Hamood
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Cube-based diffusion algorithm [PDF]

, 2007
We study molecular diffusion in (linear) nanopores with different types of roughness in the so-called Knudsen regime. Knudsen diffusion represents the limiting case of molecular diffusion in pores, where mutual encounters of the molecules within the free
Kärger, Jörg, Zschiegner, Stephan, Bunde, Armin, Russ, Stefanie   +3 more
core   +1 more source