Results 131 to 140 of about 2,387,540 (294)
Advanced Healthcare Materials, EarlyView.A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn +6 more
wiley +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
Advanced Healthcare Materials, EarlyView.LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis +8 more
wiley +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Advanced Healthcare Materials, EarlyView.Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Advanced Healthcare Materials, EarlyView.Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi +2 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A polymeric graft loaded with radiopaque bismuth nanoparticles is expected to undergo gradual polymer resorption and nanoparticle release. This design enables noninvasive, multimodal monitoring of device integrity, patency, and degradation using computed tomography alongside ultrasound and photoacoustic imaging over 12 weeks.
Allan John R. Barcena +13 more
wiley +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source