Results 51 to 60 of about 228,956 (336)

A single-center, randomized, double-blind, placebo-controlled study on the efficacy and safety of “enzyme-treated red ginseng powder complex (BG11001)” for antiwrinkle and proelasticity in individuals with healthy skin

open access: yesJournal of Ginseng Research, 2016
Background: During the aging process, skin shows visible changes, characterized by a loss of elasticity and the appearance of wrinkles due to reduced collagen production and decreased elasticity of elastin fibers.
Sang-Yong Park   +9 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Elastic modeling of point-defects and their interaction [PDF]

open access: yesComputational Materials Science, Elsevier, 2018, 147, pp.49 - 63, 2018
Different descriptions used to model a point-defect in an elastic continuum are reviewed. The emphasis is put on the elastic dipole approximation, which is shown to be equivalent to the infinitesimal Eshelby inclusion and to the infinitesimal dislocation loop.
arxiv   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Tissue elasticity and the ageing elastic fibre [PDF]

open access: yesAGE, 2009
The ability of elastic tissues to deform under physiological forces and to subsequently release stored energy to drive passive recoil is vital to the function of many dynamic tissues. Within vertebrates, elastic fibres allow arteries and lungs to expand and contract, thus controlling variations in blood pressure and returning the pulmonary system to a ...
openaire   +4 more sources

Elastic Spatial Query Processing in OpenStack Cloud Computing Environment for Time-Constraint Data Analysis

open access: yesISPRS International Journal of Geo-Information, 2017
Geospatial big data analysis (GBDA) is extremely significant for time-constraint applications such as disaster response. However, the time-constraint analysis is not yet a trivial task in the cloud computing environment. Spatial query processing (SQP) is
Wei Huang   +3 more
doaj   +1 more source

Analytical solution for the axisymmetric problem of a penny-shaped crack under internal pressure in a multi-layer composite

open access: yesMechanical Engineering Journal, 2021
The axisymmetric problem of a multi-layer composite with a penny-shaped crack, which is parallel to the interface between elastic layers, in the center plane is considered.
Kotaro MIURA   +2 more
doaj   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

Learning hidden elasticity with deep neural networks [PDF]

open access: yes, 2020
We introduce a de novo elastography method to learn the elasticity of solids from measured strains. The deep neural network in our new method is supervised by the theory of elasticity and does not require labeled data for training. Results show that the proposed method can learn the hidden elasticity of solids accurately and is robust when it comes to ...
arxiv   +1 more source

The unemployment rate in relation with the number of the economic subjects registered units

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2004
This article deals with one-factor and multiple-factor linear models definition of an unemployment rate. As the explanatory variables are considered numbers of registered units of economic subjects to thousand inhabitants separated according to the ...
Jaroslav Dufek
doaj   +1 more source

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