Results 91 to 100 of about 29,969 (357)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Alternative financial guarantees for environmental liabilities under the ELD
, 2009 This article investigates which financial mechanisms other than liability insurance can be used to guarantee the discharge of the obligations of operators liable under the EC Environmental Liability Directive (ELD).
Bocken, Hubert
core +1 more source
The relation between magnetic hysteresis and the micromagnetic state explored by quantitative magnetic force microscopy [PDF]
, 2006 Since the discovery of magnetic lodestones in 600 BC described by ancient Greek philosophers, the mystery of magnetism has continued to intrigue. For thousands of years, these lodestones were more of a curiousity until medieval explorers discovered ...
Pilet, Nicolas
core +1 more source
Navigating Peaks and Valleys - Fostering Resilience via Entrepreneurial Life Design
CERN IdeaSquare Journal of Experimental InnovationThis paper explores the integration of resilience within Entrepreneurial Life Design (ELD) in Entrepreneurship Education (EE). It examines the link between resilience and entrepreneurship, focusing on ELD to build resilience in aspiring entrepreneurs ...
Gisa Todt, Barbara Wolf, Bettina Maisch
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Eosinophil deficiency and HpARI2 treatment reduce ELD-induced lung lacunarity.
(A) Representative lung tissue sections of naïve, MF-challenged (MF), ELD, dblGATA ELD and HpARI2-treated ELD mice (ELD-HpARI) stained with hematoxylin and eosin ten days after MF challenge. (B) Lacunarity of 5 μm lung tissue sections.
Joséphine Gal (14000010) +11 more
core +1 more source
The Impact of ELD Trucking Regulations on Cattle Prices in the South [PDF]
, 2019 Anastasia W. Thayer +7 more
openalex +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source