Results 291 to 300 of about 3,202,647 (392)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Analysis of influencing factors on the nutritional status of non-dialysis elderly patients with chronic kidney disease and depression. [PDF]

World J Psychiatry
Song ZY, Li N, Liu HB.
europepmc   +1 more source

Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance

Science, 2003
K. Petersen, D. Befroy, S. Dufour, J. Dziura, C. Ariyan, D. Rothman, L. DiPietro, G. Cline, G. Shulman   +8 more
semanticscholar   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Socioeconomic inequalities in meeting the needs of the elderly in western Iran. [PDF]

BMC Public Health
Mafakheri S, Mansouri-Shad F, Cheraghi P, Nouri Q, Cheraghi Z.   +4 more
europepmc   +1 more source

Bone Tumors of the Elderly

, 1966
I. Maeyama, Seijiro Sato, Sumio Goto
openalex   +2 more sources

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

A comparison of cancellous screws in a sliding compression configuration and angle-stable sliding compression implants for internal fixation of femoral neck fractures in the non-elderly predominantly below 65 years: a systematic review and meta-analysis. [PDF]

Acta Orthop
Hansen MM, Nielsen MS, Gundtoft PH, Stilling M, Ding M, Viberg B.   +5 more
europepmc   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Exploring quality of life among elderly persons living with HIV in Accra, Ghana. [PDF]

PLoS One
Abdulai M, Teg-Nefaah Tabong P, Affran Bonful H, Addo-Lartey A, Sarfo B.   +4 more
europepmc   +1 more source