The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Self-Reported Dysphagia and Laryngopharyngeal Reflux among a Community-Dwelling Elderly Rural Population. [PDF]
Sideris G +5 more
europepmc +1 more source
Card games are effective tools to enhance foundation year health and safety inductions
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq +4 more
wiley +1 more source
Exploring loneliness in elderly Javanese and social support. [PDF]
Amalia AD, Jayaputra A, Shamadiyah N.
europepmc +1 more source
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
The mediating effect of perceived social support between e-health literacy and self-management ability in elderly stroke patients: a cross-sectional survey. [PDF]
He T +6 more
europepmc +1 more source
High prevalence of unrecognized postoperative delirium in elderly patients: a prospective cohort study from a resource-limited country. [PDF]
Nwosu ADG +4 more
europepmc +1 more source
Association between geriatric nutritional risk index (GNRI) and asthma in elderly individuals aged 60 and above: a cross-sectional study of the NHANES 2005-2018. [PDF]
Wang J, Wang Z, Zhang Q, Yu S.
europepmc +1 more source
Predictive value of frailty and nutritional status for hospital acquired pneumonia in elderly patients undergoing vascular surgeries. [PDF]
Shen L, Wang K, Wen F.
europepmc +1 more source

