Results 151 to 160 of about 6,454,237 (358)

Quantitative assessment of baseline imbalances in evolocumab and alirocumab trials: a meta-epidemiological study

BMC Medical Research Methodology
Background Baseline imbalances have been identified in randomized trials of evolocumab and alirocumab. Our aim was to quantitatively assess (1) the presence of systematic baseline differences, and (2) the relationship of baseline differences with effects
F. H. van Bruggen, S. U. Zuidema, H. J. Luijendijk   +2 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Commentary: AI-based online chat and the future of oncology care: a promising technology or a solution in search of a problem?

Frontiers in Oncology, 2023
Hui Zhang, Yongfu Guan, Jinping Chen, Wenting Tong   +3 more
doaj   +1 more source

Effects of activities participation on frailty of older adults in China

Frontiers in Public Health
ObjectiveFrailty represents a significant health challenge among older adults, necessitating effective interventions to enhance their overall wellbeing.
Zihan Ni, Xiuyuan Zhu, Yuxin Shen, Xiaoying Zhu, Xiaoying Zhu, Shiyu Xie, Xiaoguang Yang   +6 more
doaj   +1 more source

Georgia's Healthcare Inventory for the Elderly [PDF]

, 2005
This fiscal impact presents a summary of the current status of elder-care facilities and programs to provide a baseline for analyses of future pressures on healthcare facilities and programs for the elderly in ...

core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Corrigendum: Commentary: AI-based online chat and the future of oncology care: a promising technology or a solution in search of a problem?

Frontiers in Oncology, 2023
Hui Zhang, Yongfu Guan, Jinping Chen, Wenting Tong   +3 more
doaj   +1 more source

Learning From History: Deinstitutionalization of People with Mental Illness as Precursor to Long-Term Care Reform [PDF]

, 2007
Considers the deinstitutionalization of state mental hospital patients over the past fifty years, and uses this as a model for evaluating reform efforts of custodial and long-term care services for the ...
Chris Koyanagi
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Utilization of Long-Term Care by an Aging Population [PDF]

, 2018
In this brief, authors Reagan Baughman and Jon Hurdelbrink examine the relationship between macroeconomic conditions, as measured by the national unemployment rate, and utilization of long-term care, as measured by respondents’ reports in the Health and ...
Baughma, Reagan, Hurdelbrink, Jon
core   +1 more source