Results 101 to 110 of about 16,140,135 (309)

Case Report: Acupuncture for acute colonic pseudo- obstruction in a 90-year-old patient with COVID-19 infection

Frontiers in Medicine
IntroductionAcute colonic pseudo-obstruction (ACPO) is a severe gastrointestinal motility disorder defined by significant dilation of the colon without any mechanical blockage.
Binjun Liao, Meng Ren, Yang Zhao, Jun Rong   +3 more
doaj   +1 more source

Trauma in the elderly patient.

British Journal of Radiology, 2018
Angela Atinga, A. Shekkeris, M. Fertleman, N. Batrick, E. Kashef, E. Dick   +5 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Comprehensive geriatric assessment-based screening and integrated intervention for osteosarcopenia risk factors in older adults: an application analysis in patients aged ≥80 years

Zhongguo Linchuang Yixue
Objective To explore the utility of comprehensive geriatric assessment (CGA) in screening risk factors for osteosarcopenia (OS) among older adults (≥80 years old) and to evaluate the therapeutic efficacy of CGA-guided integrated interventions for OS ...
Tian ZHANG, Jiangming SHA, Liming JIANG, Quanzhong YIN, Yihang GU   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Geriatric nutritional risk index and body composition dictate the prognosis of elderly patients with intrahepatic cholangiocarcinoma

Frontiers in Nutrition
Background and aimsMalnutrition is a well-recognized predictor of poor prognosis in malignancies. Recent studies suggest that the geriatric nutritional risk index (GNRI) is a more accurate determinant of prognosis in elderly patients than conventional ...
Sheng Wang, Luo Cheng, Lei Dou, Yuanli Kuang, Yang Huang, Tao Wen, Lei Xiang, Wenyuan Xie, Cheng Zhang, Dewei Li, Hui Li   +10 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Features of the application of the digital clinical calculator of cardiovascular risk in elderly patients

Наука и инновации в медицине
Aim – evaluation of the features of using a digital clinical calculator for an objective assessment of the cardiovascular risk in elderly patients in a routine outpatient practice. Material and methods.
Nikolai A. Pervyshin
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Prediction Model of Surgical Mortality in Elderly Patient Undergoing Elective Surgery at Cipto Mangunkusumo Hospital

Jurnal Penyakit Dalam Indonesia
Introduction. Elderly patients are at high risk of mortality after elective surgery. The aim of this study was to obtain and evaluate the performance of a mortality prediction model for elderly patients undergoing elective surgery. Methods. The design
Fitria, Noto Dwimartutie, Susilo Chandra, Kuntjoro Harimurti   +3 more
doaj   +1 more source