Results 31 to 40 of about 1,319,178 (308)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

A Vote for Clarity: Establishing a Federal Test for Intervention in Election-Related Disputes [PDF]

open access: yes, 2017
Increasingly, state and federal courts are asked to resolve election-related disputes, as candidates are more likely than ever before to challenge some aspect of the administration of an election in court.
Klein, Ben
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Does Extreme Political Ideology Predict Conspiracy Beliefs, Economic Evaluations and Political Trust? Evidence From Sweden

open access: yesJournal of Social and Political Psychology, 2017
A large volume of academic research has demonstrated that individuals who profess radical political ideology, both left- and right-wing, tend to share similar underlying psychological patterns.
Andre Krouwel   +4 more
doaj   +1 more source

Challenges to Fair Elections 8: Election Day Registration Works [PDF]

open access: yes, 2006
In the final days of the 2006 campaign, as in any election year, citizen interest is peaking as election news--and debates on the issues--becomes more pervasive in the media.

core  

HOSPITAL ELECTIONS. [PDF]

open access: yesThe Lancet, 1871
n ...
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Ramshackle Federalism: America’s Archaic and Dysfunctional Presidential Election System [PDF]

open access: yes, 2016
Accordingly, this Article proposes five sensible and achievable reforms to modernize the presidential election system. Each requires Congress and the federal government to play a much more proactive role in the presidential election system.
Gaughan, Anthony J.
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Social Media and Information Integrity in Elections in Nepal

open access: yesGlobal Focus
This paper intends to explore how elections are being influenced through social media and what managerial measures have been adopted to promote information integrity in the electoral context of Nepal.
Yuba Raj Guragain
doaj   +1 more source

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