Results 61 to 70 of about 239,860 (318)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Vulnerability and adaptive capacity of fisheries-dependent communities on the Coast of Berbera to climate change

Cogent Social Sciences
Fisheries-dependent communities in the Horn of Africa, specifically Somaliland, are highly vulnerable to climate change. However, empirical research on their specific perceptions and adaptation strategies is limited.
Mohamed Abdullahi Omer, Hamud Ali Mohamoud   +1 more
doaj   +1 more source

Literasi Politik Komunitas Samin di Bojonegoro dalam Pemilu Perspektif Fiqih Siyasah

Al-Manahij: Jurnal Kajian Hukum Islam, 2020
The dynamics of political participation of the Samin community in Bojonegoro show significant development of political literacy. This study is focused on answering the political literacy of the Samin community in voicing their aspirations in the General
Muh Fathoni Hasyim
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

The closer, the better – How perceived ideological proximity between parties affects the emergence of coalition preferences

Political Research Exchange
While coalition governments have been studied extensively, there remains a lack of understanding of how coalition preferences emerge and what factors are the most influential.
L. Constantin Wurthmann, Svenja Krauss
doaj   +1 more source

Evaluating the Relationship between the Content of Bey'at in the Political Thought of Shia with the Nature and Function of Vote in Modern Constitutional Law [PDF]

پژوهش تطبیقی حقوق اسلام و غرب, 2019
In the political system of Shia, popular participation in establishment and continuity of government is based on the concept of Bey'at, which- in its most prominent model- is concluded in the form of a social contract with political agents. In modern law,
Hamed Nikonahad, mahdi zare
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

2020 Election Calendar - Statewide [PDF]

, 2020
This election calendar is broken down by date of election, election number, county, name of election, type of election, multiple county and filing ...
South Carolina State Election Commission
core  

Une modernité politique métropolitaine ? Impressions sensibles depuis Angers et Tokyo…

Métropoles, 2018
The exercise of metropolitan power immediately evokes symbols of domination and coercion, that is to say a certain form of world disenchantment. By studying what two elected metropolitan officials in Angers and Tokyo say about the sensitive motives of ...
Alain Faure
doaj   +1 more source