Results 271 to 280 of about 952,875 (360)

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Retraction notice to "Systematic literature review of postponed elections during COVID-19: Campaigns, regulations, and budgets" [Heliyon 10 (2024) e25699]. [PDF]

Heliyon
Asmorojati AW, Suyadi, Nuryana Z, Sumaryati, Megawati.   +4 more
europepmc   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Physical partisan proximity outweighs online ties in predicting US voting outcomes. [PDF]

PNAS Nexus
Tonin M, Lepri B, Tizzoni M.
europepmc   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

Advanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du, Eun Seo Bae, Thinh T. M. Bui, Seok Beom Lee, Dahan Kim, Jin‐Gyeong Park, Yongjoo Park, Soo Yeon Park, Sangwook Kang, Beomsu Lee, Daniel Shin, Yun Pyo Kang, In‐Gyun Lee, Dae‐Duk Kim, Seokhee Kim, Suckchang Hong, Kyuho Moon, Sang Kook Lee, Dong‐Chan Oh   +18 more
wiley   +1 more source

Compliant Polymeric Sheet‐Based Heat Exchangers

Advanced Science, EarlyView.
This work presents flexible, transparent, and deployable polymer heat exchangers that achieve a heat transfer capacity per cost up to 4x higher than the state of the art, surpassing both metal and other polymer counterparts. The tube‐on‐tube design enables efficient heat transfer without flow occlusion, while the lightweight, corrosion‐resistant, and ...
Richard J. Fontenot, Loic Duggal, Sofia Urbina, Barclay Jumet, Anoop Rajappan, Daniel J. Preston   +5 more
wiley   +1 more source

Application of the Three-Group Model to the 2024 US Elections. [PDF]

Entropy (Basel)
Kaufman M, Kaufman S, Diep HT.
europepmc   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Targeted digital voter suppression efforts likely decrease voter turnout. [PDF]

Proc Natl Acad Sci U S A
Kim YM, Dahlke R, Song H, Heinrich R.
europepmc   +1 more source

Cation–Anion Synergy Enables Uniform and Stable SAMs for High‐Efficiency Perovskite/TOPCon Tandem Solar Cells

Advanced Science, EarlyView.
A cation‐anion synergistic strategy is developed to enhance self‐assembled monolayer (SAM) adsorption using guanidinium thiocyanate (GuaSCN). Guanidinium (Gua⁺) suppresses micelle aggregation, while thiocyanate (SCN−) promotes phosphonic acid deprotonation and strengthens ionic bonding to the substrate.
Haofan Ma, Xin Li, Huan Li, Jianmin Guan, Luyao Zheng, Jun Wu, Ziyu He, Yunyun Yu, Jungan Wang, Jie Yang, Xinyu Zhang, Meili Zhang, Yuheng Zeng, Menglei Xu, Zhiqin Ying, Xi Yang, Jichun Ye   +16 more
wiley   +1 more source