Results 81 to 90 of about 1,219,131 (358)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Justitia Et PaxOne form of democracy's embodiment is through general elections. The Philippines and Indonesia are two countries in the Southeast Asian region that are currently still developing their democratic practices through general elections.
Janvencius Valerius Nifowa'azaro Dachi +2 more
doaj +1 more source
From 2000 Bush-Gore to 2006 Italian elections: Voting at fifty-fifty and the Contrarian Effect [PDF]
, 2007 A sociophysical model for opinion dynamics is shown to embody a series of recent western hung national votes all set at the unexpected and very improbable edge of a fifty-fifty score.
C.J. Tessone +14 more
core +4 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Election Day Registration: A Study of Voter Fraud Allegations and Findings on Voter Roll Security [PDF]
, 2007 The specter of fraud in American elections has pervaded our political and media landscape for a long time. In recent years it has been raised again as a key lever in arguments for or against certain state or federal election reforms -- in legislative and
Lorraine C. Minnite
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Российский психологический журнал, 2015 In article results of research of procedural characteristics of vital elections of the studying men and women are stated. Elections of a way of life, career and signiUcant other person act as vital elections of young people.
Юлия Валерьевна Ращупкина
doaj +1 more source
Political Institutions and Policy Outcomes: What are the Stylized Facts? [PDF]
We investigate the effect of electoral rules and political regimes on fiscal policy outcomes in a panel of 61 democracies from 1960 and onwards. In presidential regimes, the size of government is smaller and less responsive to income shocks, compared to ...
Guido Tabellini, Torsten Persson
core