Results 191 to 200 of about 2,992,832 (411)

Audit on the use of radiological investigations in the management of rhinosinusitis [PDF]

open access: yes, 2013
Objectives: The aim of this audit is to establish the cost to the Maltese health system from the use of radiological imaging in managing rhinosinusitis and to identify areas in which these costs can be minimised by following guidelines on the management ...
Borg-Xuereb, Hermann K.   +2 more
core  

A multi-centre prospective cohort study of patients on the elective waiting list for cardiac surgery during the COVID-19 pandemic [PDF]

open access: bronze, 2022
Martin T. Yates   +10 more
openalex   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu   +12 more
wiley   +1 more source

Variability in Exposure to Subspecialty Rotations During Orthopaedic Residency: A Website-based Review of Orthopaedic Residency Programs. [PDF]

open access: yes, 2019
IntroductionThe variability in exposure to various subspecialty rotations during orthopaedic residency across the United States has not been well studied.MethodsData regarding program size, resident's sex, department leadership, university-based status ...
Chan, Jason   +3 more
core   +1 more source

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

open access: yesAdvanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo   +14 more
wiley   +1 more source

Race based disparities in clinical and financial outcomes associated with major elective and emergent surgery

open access: yesSurgery Open Science
Background: Racial health disparities are responsible for ∼$50 billion in excess annual healthcare expenditures, driven in part by unequal access to preventive services. We thus studied cost differences in abdominal aortic aneurysm repair (AAA), coronary
Saad Mallick, MD   +6 more
doaj   +1 more source

The use of remifentanil without muscle relaxant for intubation in short-timed, elective surgeries

open access: diamond, 2020
Tjokorda Gde Agung Senapathi   +5 more
openalex   +1 more source

METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation

open access: yesAdvanced Science, EarlyView.
METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li   +19 more
wiley   +1 more source

Optimizing timing for elective surgery in cancer patients following COVID-19 infection; a post-pandemic analysis

open access: yesInfectious Agents and Cancer
Introduction The COVID-19 pandemic introduced challenges including delaying elective surgery. For cancer patients, reducing delays is preferred to prevent unfavorable outcomes. there is a lack of consensus regarding the optimal timing of elective surgery
Mahmoud Al-Masri   +6 more
doaj   +1 more source

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