Results 101 to 110 of about 165,588 (337)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Modern concepts in non-surgical esthetics; a review [PDF]

, 2019
New non-surgical esthetics is the most dynamic field in contemporary medicine. At the same time, it is greatly influenced by our contemporary society. This paper reviews modern methods used in non-surgical esthetics, especially in Romania.
Andronache, Liliana F, Balalau, Cristian, Hainarosie, Razvan, Paunica, Stana, Pietrosanu, Catalina, Pituru, Teodora S, Rusescu, Andreea, Stoian, Anca Pantea   +7 more
core   +3 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Current Strategies in Prevention of Postoperative Infections in Spine Surgery. [PDF]

, 2020
Study Design: Narrative review. Objectives: Postoperative surgical site infections (SSIs) are among the most common acute complications in spine surgery and have a devastating impact on outcomes. They can lead to increased morbidity and mortality as well
Atesok, Kivanc, Gokaslan, Ziya L, Heffernan, Michael J, Papavassiliou, Efstathios, Pittman, Jason, Rajaram, Sakthivel, Sitnikov, Irina, Tanaka, Nobuhiro, Theiss, Steven, Tunmire, Danny, Vaccaro, Alexander   +10 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

ANALYSIS OF THE DYNAMICS OF SURGICAL TREATMENT OF HEMORRHOIDS IN MEDICAL ORGANIZATIONS IN ALMATY IN 2012-2021

Актуальные проблемы теоретической и клинической медицины
Relevance. Hemorrhoids are among the most common anorectal diseases and remain an important clinical and organizational challenge in modern coloproctology.
B. S. Baimanov, M. K. Kulzhanov, A. T. Dzhumabekov, A. K. Baimanova, M. Z. Sarsenbayeva   +4 more
doaj   +1 more source

Anxiety and pain in children undergoing elective surgical procedures: a systematic review

JBI Database of Systematic Reviews and Implementation Reports, 2010
Anxiety and pain are two significant problems experienced by children undergoing elective surgical procedures, which may lead to suboptimal postoperative outcomes. Previous studies have shown a correlation between perioperative anxiety and pain in children.This review aimed to present the best available evidence on the correlation between perioperative
Chieng, Ying Jia Shermin, Chan, Sally Wai-Chi, He, Hong-Gu   +2 more
openaire   +5 more sources

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Economic evaluation of the proposed surgical scheme at Auburn Hospital: Final report, CHERE Project Report No 19 [PDF]

Background Public hospitals have experienced budget constraints but as demand for admissions has been growing at the same time, occupancy levels have been increasing.
Christine Pollicino, Jane Hall, Phil Haywood   +2 more
core