Results 161 to 170 of about 147,993 (217)
ABSTRACT Background The pathogenesis of inflammation in eosinophilic chronic rhinosinusitis (ECRS) and non‐eosinophilic chronic rhinosinusitis (NECRS) remains poorly understood. This study aimed to assess immune cell infiltration within the sinonasal microenvironment in these conditions.
Katarzyna Czerwaty+5 more
wiley +1 more source
ABSTRACT Background Temperature‐controlled radiofrequency (TCRF) ablation of the posterior nasal nerve has been shown to improve chronic rhinitis (CR) symptoms and quality of life (QoL). This study assesses the durability of TCRF's effectiveness and safety 3 years post‐procedure in patients with perennial allergic CR and nonallergic CR.
J. Pablo Stolovitzky+8 more
wiley +1 more source
ABSTRACT Background Particulate matter ⩽2.5 µm in diameter (PM2.5) and its role in chronic rhinosinusitis (CRS) pathogenesis have gained heightened attention. We previously demonstrated that PM2.5 exposure may bias the nasal mucosa in CRS toward a Type 2 inflammatory pathway.
Rory J. Lubner+5 more
wiley +1 more source
ABSTRACT Background Olfactory dysfunction affects up to 22% of the population. Accurate assessment is vital for diagnosis and tracking outcomes, often using patient‐reported outcome measures (PROMs). Aims We aimed to develop and validate a novel questionnaire for assessing olfactory and gustatory dysfunction.
Matt Lechner+31 more
wiley +1 more source
Aziridination of alkenes is an important route to chiral nitrogen‐containing building blocks. We report that carbamate‐functionalized allylic alcohols undergo highly enantioselective aziridination using achiral dimeric Rh complexes ion‐paired with cinchona alkaloid‐derived chiral cations.
Arthur R. Lit+4 more
wiley +2 more sources
Premenopausal bilateral oophorectomy and Alzheimer's disease imaging biomarkers later in life
Abstract INTRODUCTION Premenopausal bilateral oophorectomy (PBO) before the age of 46 years is associated with an increased risk of dementia. We investigated the long‐term effects of PBO performed before age 50 years on amyloid beta (Aβ), tau, and neurodegeneration imaging biomarkers of Alzheimer's disease (AD).
Kejal Kantarci+13 more
wiley +1 more source
Objectives Rapid advances in transcriptomics have driven efforts to identify deregulated pathways in multiple sclerosis (MS) tissues, though many detected differentially expressed genes are likely false positives, with only a small fraction reflecting actual pathological events. Robust, integrative methods are essential for accurately understanding the
Gianmarco Abbadessa+11 more
wiley +1 more source
Impact of COVID-19 on Surgical Procedural Utilization. [PDF]
Nehila TE+3 more
europepmc +1 more source
Improving the quality of discharge summaries for elective surgical procedures at North Bristol NHS Trust. [PDF]
Ladds E+3 more
europepmc +1 more source