Results 201 to 210 of about 165,009 (328)

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

open access: yesAdvanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli   +16 more
wiley   +1 more source

Impact of the COVID-19 Pandemic on Elective and Emergency Surgeries, and Postoperative Mortality in a Brazilian Metropolitan Area: A Time-Series Cohort Study

open access: yesRisk Management and Healthcare Policy
Dilson Palhares Ferreira,1,* Claudia Vicari Bolognani,2,3,* Levy Aniceto Santana,2,* Sergio Eduardo Soares Fernandes,2,3,* Matheus Serwy Fiuza de Moraes,3,* Luana Argollo Souza Fernandes,3,* Daniella Queiroz de Oliveira,3,&ast ...
Ferreira DP   +9 more
doaj  

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

open access: yesAdvanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol   +17 more
wiley   +1 more source

The Cost Effectiveness of Elective Surgical Procedures with Longer NHS Waiting Lists: A Targeted Review. [PDF]

open access: yesAppl Health Econ Health Policy
Trigg LA   +5 more
europepmc   +1 more source

Pulmonary Complications After Cardiac Surgical Procedures: A Tertiary Centre Audit of Elective and Urgent Cases

open access: diamond
Usha Gurunathan   +5 more
openalex   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

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