Results 41 to 50 of about 1,307,349 (312)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Multi-Objective in Mapping the Optimal Distributed Generation Configuration through GWOA to Enhance Grid Performance Reliability

open access: yesJurnal Rekayasa Elektrika
In electric power distribution systems, the distance between the load bus and the generating unit significantly affects grid efficiency and reliability, with longer distances causing greater voltage drops. To mitigate this, Distributed Generation (DG) is
I Gede Putu Oka Indra Wijaya   +3 more
doaj   +1 more source

Identification of mechanical impedance of an electric machine drive for drivetrain design

open access: yes, 2023
This paper proposes a method for identifying mechanical impedance of an electric machine drive for drivetrain design and analysis. The mechanical impedance describes the dynamics of an electric machine as seen from its mechanical terminals.
Laine, Sampo   +3 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The Effect of Conductor Sag on EMF Exposure Assessment for 400 kV Double-Bundle

open access: yesApplied Sciences
This study investigates the effect of seasonal conductor sag on electromagnetic field (EMF) exposure to near 400 kV double-bundle overhead transmission lines. The conductor sag study resulted in clearance values of 28.0 m for winter (−10 °C, sag ≈ 7.0 m)
Kjani Guri   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

URBAN ELECTRIC TRICYCLE

open access: yesJournal of Industrial Design and Engineering Graphics, 2019
An important play in an economic development and evolution of a country has the field of transportation. In most countries, transportation with personal car has started to become a problem, the streets are far too small and narrow for the large number of
Andrei Toanchina
doaj   +2 more sources

Modeling of pulsed electric field processing

open access: yesFood Innovation and Advances, 2023
Herein, we discuss the modeling of the pulsed electric field (PEF) process, with attention focused on the originally intended application of pasteurization of liquid foods. We review literature on three classes of models.
Sudhir K. Sastry
doaj   +1 more source

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