Results 41 to 50 of about 100,694 (311)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Brushless DC Motor Current Prediction Torque Ripple Suppression

Journal of Harbin University of Science and Technology, 2020
Aiming at the torque ripple problem of brushless DC motor, a current predictive control method combined with commutation overlap method is proposed to suppress the commutation torque ripple Based on the analysis of the cause of the commutation torque ...
LDegang, ZHANG Chenguang, HOU Zhengdong
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Design issues of an IPM motor for EPS [PDF]

, 2011
In electric power steering (EPS), permanent magnet (PM) brushless ac (BLAC) motors offer distinct advantages over other electric motor types in terms torque smoothness, reliability and efficiency.
Shen, Jian-Xin, Luk, Patrick Chi-Kwong, Wang, Can-Fei, Fei, Wei-Zhong, Jin, Meng-Jia   +4 more
core   +1 more source

Electromagnetic Analysis and Optimization of Ferrite-Assisted Double-Layer Halbach Permanent–Magnet Vernier Motor Based on Improved Cuckoo Search Grey Wolf Optimization Algorithm

IET Electrical Systems in Transportation
In order to improve the electromagnetic torque and stability of the drive motor for belt conveyors, and considering economic benefits, two ferrite assisted double-layer nonuniform Halbach array consequent-pole (DNHC-permanent magnet synchronous motors ...
Pin Lv, Haotian Ma, Rui Li, Xunwen Su, Ziyang Liu, Lulu Liu, Donghui Xu   +6 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Electric propeller drive based on a reactive electric machine for ice-class ships [PDF]

The article presents the results of theoretical and experimental studies of a propulsion electric drive based on reactive electric machines with anisotropic magnetic conductivity of the rotor of a wide power range from 1.5 kW to 1.7 MW.
I.V. Belousov, A.V. Saushev, F. A. Gelver, V.F. Samoseiko   +3 more
core   +1 more source

Design of LLC Magnetically Integrated Transformer Based on Nanocrystalline Soft Magnetic Composite Leakage Core

CES Transactions on Electrical Machines and Systems
Magnetic integration technology can reduce the printed circuit board (PCB) size of inductor-inductor-capacitor (LLC) converters. However, conventional methods for adjusting leakage inductance by modifying the transformer's air gap exhibit low sensitivity
Kaimeng Shi, Dianhai Zhang, Xuanzhe Zhao, Ziyan Ren   +3 more
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Influence of Rotor Structure and Number of Phases on Torque and Flux Weakening Characteristics of V-Shape Interior PM Electrical Machine [PDF]

, 2011
Post publication CONGRES EVER2011 (International Conference and Exhibition on Ecological Vehicles and Renewable Energies 2011)This paper investigates the influence of the rotor structure on torque and flux weakening region of V-shape IPM (interior ...
VIGIER, Thimoté, KORECKI, Julien, ASLAN, Bassel, SEMAIL, Eric, Vigier, Thimotee   +4 more
core