Results 211 to 220 of about 64,731 (311)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

The impact of AI on Japanese language education: a hybrid model for student behavior detection. [PDF]

Sci Rep
Li Y, Zou H, Xu J, Chen D, Zhou Y, Liu Y.   +5 more
europepmc   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Novel Method for Recording and Classifying Electric Organ Discharges from Freely Swimming Mormyrid Weakly Electric Fish

, 2018
Snigdha Srivastava
openalex   +1 more source

Interactions in the Frequencies of Electric Organ Discharge by Eigenmannia Virescens (Sternopygidae, Pisces) During Social Behavior

, 2000
Philip K. Gaddis
openalex   +2 more sources

Decision letter for "Ontogeny of the electric organ discharge and of the papillae of the electrocytes in the weakly electric fish <scp> <i>Campylomormyrus rhynchophorus</i> </scp> (Teleostei: Mormyridae)"

, 2020

openalex   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

The SIS NET ICU study: characteristics of patients with severe community acquired pneumonia admitted to Italian ICUs-a multicenter prospective observational study. [PDF]

J Anesth Analg Crit Care
Ippolito M, Catalisano G, Velardo M, Campione M, Damiano M, Bocci MG, Camilloni B, Cocuzza C, Comar M, De Robertis E, Fasciana TMA, Fumagalli R, Giammanco GM, Girardis M, Marchese A, Panascia E, Pace MC, di Villalba CP, Patroniti N, Roman-Pognuz E, Raineri SM, Romagnoli S, Spadaro S, Terragni P, Uzzau S, Vaschetto R, Cortegiani A, Giarratano A, S I S-N E T I C U Study Group.   +28 more
europepmc   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

A chromosome-level genome assembly of Electrophorus voltai, a species of electric eel. [PDF]

Sci Data
Wang Y, Liu Y, Yang Y, Bian C, Liu C, Zhang Y, Mu X.   +6 more
europepmc   +1 more source